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WISP3 Antikörper (AA 221-320) (Biotin)

WISP3 Reaktivität: Ratte WB, ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN1700981
  • Target Alle WISP3 Antikörper anzeigen
    WISP3 (Wnt1 Inducible Signaling Pathway Protein 3 (WISP3))
    Bindungsspezifität
    • 14
    • 7
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 221-320
    Reaktivität
    • 25
    • 15
    • 2
    Ratte
    Wirt
    • 38
    • 1
    Kaninchen
    Klonalität
    • 39
    Polyklonal
    Konjugat
    • 11
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser WISP3 Antikörper ist konjugiert mit Biotin
    Applikation
    • 29
    • 15
    • 13
    • 13
    • 9
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Ratte
    Homologie
    Human,Mouse,Dog,Sheep,Horse,Rabbit,Monkey
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human WISP3
    Isotyp
    IgG
    Top Product
    Discover our top product WISP3 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    WISP3 (Wnt1 Inducible Signaling Pathway Protein 3 (WISP3))
    Andere Bezeichnung
    WISP3 (WISP3 Produkte)
    Synonyme
    CCN6 antikoerper, LIBC antikoerper, PPAC antikoerper, PPD antikoerper, ENSMUSG00000062074 antikoerper, Gm735 antikoerper, WISP-3 antikoerper, RGD1564120 antikoerper, WISP3 antikoerper, si:dkey-119m7.6 antikoerper, WNT1 inducible signaling pathway protein 3 antikoerper, WISP3 antikoerper, Wisp3 antikoerper, wisp3 antikoerper
    Hintergrund

    Synonyms: CCN 6, CCN family member 6, CCN6, CYR61, LIBC, Lost in inflammatory breast cancer tumor suppressor protein, MGC125987, MGC125988, MGC125989, OTTHUMP00000040421, PPAC, PPD, UNQ462/PRO790/PRO956, WISP 3, WISP-3, WISP3, WISP3_HUMAN, WNT 1 inducible signaling pathway protein 3, Wnt 1 signaling pathway protein 3, WNT1 inducible signaling pathway protein 3, WNT1 inducible signaling pathway protein 3 precursor, WNT1-inducible-signaling pathway protein 3.

    Background: Wnt-induced secreted protein (WISP)-1, WISP-2 and WISP-3 are members of the CCN family of growth factors, which include connective tissue growth factor (CTGF) and Cyr61. WISP-1, WISP-2 and WISP-3 share significant sequence similarity, including four conserved cysteine-rich domains, and they are believed to function as dimers in their active forms. WISP-1 expression is observed in various tissues including adult heart, kidney and spleen, while WISP-2 expression predominates in skeletal muscle, colon and ovary. Both WISP-1 and WISP-2 are upregulated in cells transformed with the proto-oncogene Wnt-1, and they are also more highly expressed in human colon tumors, suggesting that these proteins may participate in tumor development. WISP-3 is involved in normal post-natal skeletal growth, and it is also implicated in the development of the autosomal recessive skeletal disorder progressive pseudorheumatoid dysplasia, which affects cartilage homeostasis by disrupting the growth of chondrocyte and normal cell columnar organization.

    Gen-ID
    8838
    Pathways
    WNT Signalweg, Growth Factor Binding
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