WISP3 Antikörper (AA 42-260)

Produktnummer ABIN7271384

Der Kaninchen Polyklonal anti-WISP3 Antikörper wird verwendet zum Nachweis von WISP3 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für WISP3 Antikörper (AA 42-260) (ABIN7271384)

Target: WISP3 (Wnt1 Inducible Signaling Pathway Protein 3 (WISP3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WISP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-WISP3 Antikörper

Bindungsspezifität: AA 42-260

Verwendungszweck: WISP3 Rabbit pAb

Sequenz: TGPLDTTPEG RPGEVSDAPQ RKQFCHWPCK CPQQKPRCPP GVSLVRDGCG CCKICAKQPG EICNEADLCD PHKGLYCDYS VDRPRYETGV CAYLVAVGCE FNQVHYHNGQ VFQPNPLFSC LCVSGAIGCT PLFIPKLAGS HCSGAKGGKK SDQSNCSLEP LLQQLSTSYK TMPAYRNLPL IWKKKCLVQA TKWTPCSRTC GMGISNRVTN ENSNCEMRK

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 42-260 of human WISP3 (NP_937882.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu WISP3

Target: WISP3 (Wnt1 Inducible Signaling Pathway Protein 3 (WISP3))

Andere Bezeichnung: WISP3

Hintergrund: This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. This gene is overexpressed in colon tumors. It may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Mutations of this gene are associated with progressive pseudorheumatoid dysplasia, an autosomal recessive skeletal disorder, indicating that the gene is essential for normal postnatal skeletal growth and cartilage homeostasis. Multiple transcript variants encoding different isoforms have been found for this gene.,WISP3,CCN6,LIBC,PPAC,PPD,WISP-3,Cell Biology & Developmental Biology,Growth factor,Immunology & Inflammation,Stem Cells,Mesenchymal Stem Cells,WISP3

Molekulargewicht: 39kDa/41kDa

Gen-ID: 8838

UniProt: O95389

Pathways: WNT Signalweg, Growth Factor Binding