WISP3 Antikörper (AA 1-50)

Produktnummer ABIN7227052

Der Kaninchen Polyklonal anti-WISP3 Antikörper (ABIN7227052) detektiert spezifisch WISP3 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für WISP3 Antikörper (AA 1-50) (ABIN7227052)

Target: WISP3 (Wnt1 Inducible Signaling Pathway Protein 3 (WISP3))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WISP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-WISP3 Antikörper

Bindungsspezifität: AA 1-50

Verwendungszweck: Rabbit Anti-WISP-3 Polyclonal Antibody

Spezifität: The antibody detects endogenous WISP-3.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthetic peptide from human protein at AA range: 1-50

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:10000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu WISP3

Target: WISP3 (Wnt1 Inducible Signaling Pathway Protein 3 (WISP3))

Andere Bezeichnung: WISP-3

Hintergrund: WNT1-inducible-signaling pathway protein 3, WISP-3, CCN family member 6WISP3 (WNT1 inducible signaling pathway protein 3) encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. WISP3 is overexpressed in colon tumors. It may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Mutations of WISP3 are associated with progressive pseudorheumatoid dysplasia, an autosomal recessive skeletal disorder, indicating that the gene is essential for normal postnatal skeletal growth and cartilage homeostasis. Multiple transcript variants encoding different isoforms have been found for WISP3.

Molekulargewicht: 55kD

Gen-ID: 8838

UniProt: O95389

Pathways: WNT Signalweg, Growth Factor Binding