KHDRBS1 Antikörper (AA 101-200) (Alexa Fluor 647)

Produktnummer ABIN1698914

Produktdetails anti-KHDRBS1 Antikörper (Alexa Fluor 647)

Target: KHDRBS1 (KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1))

Bindungsspezifität: AA 101-200

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KHDRBS1 Antikörper ist konjugiert mit Alexa Fluor 647

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SAM68

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu KHDRBS1

Target: KHDRBS1 (KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1))

Andere Bezeichnung: Sam68 (KHDRBS1 Produkte)

Synonyme: Sam68 antikoerper, p62 antikoerper, p68 antikoerper, fj90g10 antikoerper, khdrbs1 antikoerper, wu:fa18g12 antikoerper, wu:fa56c01 antikoerper, wu:fc91b01 antikoerper, wu:fj90g10 antikoerper, zgc:113899 antikoerper, KHDRBS1 antikoerper, P62 antikoerper, khdrbs1l antikoerper, sb:cb97 antikoerper, wu:fb07d11 antikoerper, wu:fi43c05 antikoerper, zgc:85948 antikoerper, KH RNA binding domain containing, signal transduction associated 1 antikoerper, KH domain containing, RNA binding, signal transduction associated 1a antikoerper, KH domain containing, RNA binding, signal transduction associated 1 antikoerper, KH domain containing, RNA binding, signal transduction associated 1 S homeolog antikoerper, KH domain containing, RNA binding, signal transduction associated 1b antikoerper, KHDRBS1 antikoerper, khdrbs1a antikoerper, khdrbs1 antikoerper, Khdrbs1 antikoerper, khdrbs1.S antikoerper, khdrbs1b antikoerper

Hintergrund:

Synonyms: FLJ34027, GAP associated tyrosine phosphoprotein p62, GAP-associated tyrosine phosphoprotein p62, KH domain containing RNA binding signal transduction associated 1, KH domain-containing, KHDR1_HUMAN, KHDRBS1, p21 Ras GTPase activating protein associated p62, p21 Ras GTPase-activating protein-associated p62, p62, p68, RNA-binding, Sam68, signal transduction-associated protein 1, Src associated in mitosis 68 kDa protein, Src-associated in mitosis 68 kDa protein.

Background: Sam 68 is a protein that is phosphorylated on tyrosine and functions as a substrate for Src family tyrosine kinases during mitosis. Sam 68 also associates with several SH2 and SH3 domain-containing signaling proteins, such as GRB2 and PLC ?. Originally cloned as Ras GAP-associated p62, further investigations have shown that Sam 68 and Ras GAP-associated p62 are not antigenically related, nor are they encoded by the same gene. Like Sam 68, the Sam 68-like mammalian proteins, SLM-1 and SLM-2, demonstrate RNA binding activity. Also like Sam 68, SLM-1 is tyrosine phosphorylated and functions as an adapter protein for signaling molecules, including GRB2, PLC ?, Fyn and Ras GAP. SLM-2 is not tyrosine phosphorylated, nor does it appear to associate with GRB2, PLC ?, Fyn or Ras GAP, indicating that SLM-2 may not be an adapter protein for these proteins.

Pathways: NF-kappaB Signalweg, Neurotrophin Signalübertragung, Autophagie