IL-10 Antikörper
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- Target Alle IL-10 (IL10) Antikörper anzeigen
- IL-10 (IL10) (Interleukin 10 (IL10))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser IL-10 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Aufreinigung
- Purified
- Sterilität
- Sterile filtered
- Immunogen
- Polyclonal Interleukin-10 antibody was produced from sera of rabbits immunized with synthetic protein containing Interleukin-10 antigenic determinants.
- Isotyp
- IgG
- Top Product
- Discover our top product IL10 Primärantikörper
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- Applikationshinweise
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ELISA: Use at a concentration range of 1-2 µg/mL.
Western blot: A suitable range of concentrations of this antibody for WB detection is 10 µg/mL.
IHC: A suitable range of concentrations of this antibody for IHC is 10 µg/mL. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- A quick spin of the vial followed by reconstitution in distilled water. This solution can then be diluted into other buffers
- Buffer
- PBS solution at a concentration of 1 mg/mL.
- Handhabung
- Avoid repeated freeze/thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Recombinant CD80, as supplied, can be stored in working aliquots at - 8 °C for one month, or at -20 °C to -70 °C for twelve months.
- Haltbarkeit
- 12 months
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- Target
- IL-10 (IL10) (Interleukin 10 (IL10))
- Andere Bezeichnung
- IL-10 (IL10 Produkte)
- Synonyme
- CSIF antikoerper, GVHDS antikoerper, IL-10 antikoerper, IL10A antikoerper, TGIF antikoerper, Il-10 antikoerper, IL10X antikoerper, interleukin 10 antikoerper, IL10 antikoerper, Il10 antikoerper
- Hintergrund
- CD80 is a monomeric surface protein found on activated APCs. The extracellular region of CD80 consists of two highly glycosylated Ig-like extracellular domains, which have defined regions for binding its ligands, CD28 or CTLA-4, on T cells. One ligand of CD80, CD28, provides critical costimulatory signals to activated T cells to increase cytokine production, cell proliferation, and cell viability, while the other ligand, CTLA-4, may mediate a growth-inhibitory signal. The same regions of CD80 are involved in binding to both CD28 and CTLA-4, but CTLA-4 binds to CD80 with about a0-fold higher avidity than CD28 does. This suggests that low levels of CTLA-4 expressed on the cell surface can compete for CD80 binding even when CD28 is expressed at much higher levels.
- UniProt
- P22301
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints
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