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IL-10 Antikörper (AA 27-53)

IL10 Reaktivität: Human WB, ELISA, IHC, FACS Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3031441
  • Target Alle IL-10 (IL10) Antikörper anzeigen
    IL-10 (IL10) (Interleukin 10 (IL10))
    Bindungsspezifität
    • 37
    • 16
    • 16
    • 7
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 27-53
    Reaktivität
    • 153
    • 95
    • 51
    • 19
    • 17
    • 11
    • 8
    • 7
    • 7
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 124
    • 79
    • 64
    • 4
    • 3
    • 1
    Kaninchen
    Klonalität
    • 142
    • 127
    • 1
    Polyklonal
    Konjugat
    • 169
    • 35
    • 12
    • 11
    • 8
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Dieser IL-10 Antikörper ist unkonjugiert
    Applikation
    • 169
    • 125
    • 80
    • 69
    • 43
    • 29
    • 28
    • 19
    • 17
    • 15
    • 15
    • 14
    • 14
    • 13
    • 12
    • 8
    • 7
    • 7
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
    Kreuzreaktivität (Details)
    Expected species reactivity: Primate
    Aufreinigung
    Antigen affinity purified
    Immunogen
    A portion of amino acids 27-53 from the human protein was used as the immunogen for this IL-10 antibody.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product IL10 Primärantikörper
  • Applikationshinweise
    Titration of the IL-10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot the IL-10 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    IL-10 (IL10) (Interleukin 10 (IL10))
    Andere Bezeichnung
    IL-10 (IL10 Produkte)
    Synonyme
    CSIF antikoerper, GVHDS antikoerper, IL-10 antikoerper, IL10A antikoerper, TGIF antikoerper, Il-10 antikoerper, IL10X antikoerper, interleukin 10 antikoerper, IL10 antikoerper, Il10 antikoerper
    Hintergrund
    The protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.
    UniProt
    P22301
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints
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