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MBD2 Antikörper (AA 202-411)

MBD2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1680781
  • Target Alle MBD2 Antikörper anzeigen
    MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))
    Bindungsspezifität
    • 9
    • 8
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 202-411
    Reaktivität
    • 47
    • 23
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 44
    • 2
    • 1
    Kaninchen
    Klonalität
    • 44
    • 3
    Polyklonal
    Konjugat
    • 25
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MBD2 Antikörper ist unkonjugiert
    Applikation
    • 40
    • 22
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    DLSSFDFRTG KMMPSKLQKN KQRLRNDPLN QNKGKPDLNT TLPIRQTASI FKQPVTKVTN HPSNKVKSDP QRMNEQPRQL FWEKRLQGLS ASDVTEQIIK TMELPKGLQG VGPGSNDETL LSAVASALHT SSAPITGQVS AAVEKNPAVW LNTSQPLCKA FIVTDEDIRK QEERVQQVRK KLEEALMADI LSRAADTEEM DIEMDSGDEA
    Kreuzreaktivität
    Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 202-411 of human MBD2 (NP_003918.1).
    Isotyp
    IgG
    Top Product
    Discover our top product MBD2 Primärantikörper
  • Applikationshinweise
    WB,1:200 - 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))
    Andere Bezeichnung
    MBD2 (MBD2 Produkte)
    Synonyme
    MBD2 antikoerper, DMTase antikoerper, NY-CO-41 antikoerper, MBD2a antikoerper, wu:fa97f06 antikoerper, zgc:111862 antikoerper, methyl-CpG binding domain protein 2 antikoerper, methyl-CpG binding domain protein 2 S homeolog antikoerper, MBD2 antikoerper, Mbd2 antikoerper, mbd2 antikoerper, mbd2.S antikoerper
    Hintergrund
    DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. The protein encoded by this gene may function as a mediator of the biological consequences of the methylation signal. It is also reported that the this protein functions as a demethylase to activate transcription, as DNA methylation causes gene silencing. Two transcript variants encoding different isoforms have been found for this gene.,MBD2,DMTase,NY-CO-41,Epigenetics & Nuclear Signaling,MBD2
    Molekulargewicht
    31 kDa/43 kDa
    Gen-ID
    8932
    UniProt
    Q9UBB5
    Pathways
    Chromatin Binding
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