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MBD2 Antikörper (Center)

MBD2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2856140
  • Target Alle MBD2 Antikörper anzeigen
    MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))
    Bindungsspezifität
    • 10
    • 8
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reaktivität
    • 49
    • 24
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 46
    • 2
    • 1
    Kaninchen
    Klonalität
    • 45
    • 4
    Polyklonal
    Konjugat
    • 27
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MBD2 Antikörper ist unkonjugiert
    Applikation
    • 42
    • 22
    • 6
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Kreuzreaktivität
    Maus, Ratte (Rattus), Xenopus laevis
    Kreuzreaktivität (Details)
    Mouse (98 %), Rat (98 %), Xenopus laevis (89 %)
    Produktmerkmale
    Rabbit polyclonal antibody to MBD2 (methyl-CpG binding domain protein 2)
    MBD2 antibody [N2C3]
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human MBD2. The exact sequence is proprietary.
    Isotyp
    IgG
    Top Product
    Discover our top product MBD2 Primärantikörper
  • Applikationshinweise
    Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*
    Kommentare

    Positive Control: A431 , Jurkat , Raji

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.48 mg/mL
    Buffer
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))
    Andere Bezeichnung
    MBD2 (MBD2 Produkte)
    Synonyme
    MBD2 antikoerper, DMTase antikoerper, NY-CO-41 antikoerper, MBD2a antikoerper, wu:fa97f06 antikoerper, zgc:111862 antikoerper, methyl-CpG binding domain protein 2 antikoerper, methyl-CpG binding domain protein 2 S homeolog antikoerper, MBD2 antikoerper, Mbd2 antikoerper, mbd2 antikoerper, mbd2.S antikoerper
    Hintergrund
    DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. The protein encoded by this gene may function as a mediator of the biological consequences of the methylation signal. It is also reported that the this protein functions as a demethylase to activate transcription, as DNA methylation causes gene silencing.

    Cellular Localization: Nucleus
    Molekulargewicht
    43 kDa
    Gen-ID
    8932
    Pathways
    Chromatin Binding
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