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PIDD Antikörper (AA 1-85)

PIDD Reaktivität: Human IHC, WB, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1680710
  • Target Alle PIDD Antikörper anzeigen
    PIDD (P53-Induced Death Domain Protein (PIDD))
    Bindungsspezifität
    • 15
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-85
    Reaktivität
    • 20
    • 19
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 33
    • 3
    Kaninchen
    Klonalität
    • 33
    • 3
    Polyklonal
    Konjugat
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PIDD Antikörper ist unkonjugiert
    Applikation
    • 13
    • 13
    • 13
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)
    Sequenz
    MAATVEGPEL EAAAAAGDAS EDSDAGSRAL PFLGGNRLSL DLYPGGCQQL LHLCVQQPLQ LLQVEFLRLS THEDPQLLEA TLAQL
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-85 of human PIDD (NP_665893.2).
    Isotyp
    IgG
  • Applikationshinweise
    WB,1:500 - 1:1000,IHC,1:50 - 1:200,IF,1:50 - 1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    PIDD (P53-Induced Death Domain Protein (PIDD))
    Andere Bezeichnung
    PIDD (PIDD Produkte)
    Synonyme
    1200011D09Rik antikoerper, AU042446 antikoerper, Pidd antikoerper, LRDD antikoerper, Lrdd antikoerper, p53 induced death domain protein 1 antikoerper, p53-induced death domain protein 1 antikoerper, Pidd1 antikoerper, PIDD1 antikoerper
    Hintergrund
    The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Alternative splicing results in multiple transcript variants.,PIDD1,LRDD,PIDD,Cancer,Tumor suppressors,p53 pathway,Cell Biology & Developmental Biology,Apoptosis,Mitochondrial Control of Apoptosis,PIDD
    Molekulargewicht
    33 kDa/37 kDa/58 kDa/66 kDa/82 kDa/97 kDa/99 kDa
    Gen-ID
    55367
    UniProt
    Q9HB75
    Pathways
    p53 Signalweg, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity
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