PIDD Antikörper (AA 776-910)

Produktnummer ABIN7193396

Produktdetails anti-PIDD Antikörper

Target: PIDD (P53-Induced Death Domain Protein (PIDD))

Bindungsspezifität: AA 776-910

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PIDD Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS), Neutralization (Neut)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human PIDD1 (AA: 776-910) expressed in E. coli.

Klon: 3C5G8

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: N/A, ICC: N/A, IHC: N/A

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Details zu PIDD

Target: PIDD (P53-Induced Death Domain Protein (PIDD))

Andere Bezeichnung: PIDD1 (PIDD Produkte)

Synonyme: 1200011D09Rik antikoerper, AU042446 antikoerper, Pidd antikoerper, LRDD antikoerper, Lrdd antikoerper, p53 induced death domain protein 1 antikoerper, p53-induced death domain protein 1 antikoerper, Pidd1 antikoerper, PIDD1 antikoerper

Hintergrund:

Description: The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010]

Aliases: LRDD, PIDD

Molekulargewicht: 99.7 kDa

Gen-ID: 55367

Pathways: p53 Signalweg, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity