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PIDD Antikörper

PIDD Reaktivität: Maus WB Wirt: Maus Monoclonal Lise-1 unconjugated
Produktnummer ABIN1169269
  • Target Alle PIDD Antikörper anzeigen
    PIDD (P53-Induced Death Domain Protein (PIDD))
    Reaktivität
    • 20
    • 20
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 34
    • 2
    Maus
    Klonalität
    • 34
    • 2
    Monoklonal
    Konjugat
    • 15
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PIDD Antikörper ist unkonjugiert
    Applikation
    • 13
    • 13
    • 13
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Spezifität
    Recognizes mouse PIDD.
    Kreuzreaktivität
    Maus
    Aufreinigung
    Purified from concentrated hybridoma tissue culture supernatant.
    Reinheit
    >95 % (SDS-PAGE)
    Immunogen
    Mouse PIDD (Death Domain).
    Klon
    Lise-1
    Isotyp
    IgG2b
    Top Product
    Discover our top product PIDD Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    In PBS containing 10 % glycerol and 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.
    Haltbarkeit
    12 months
  • Target
    PIDD (P53-Induced Death Domain Protein (PIDD))
    Andere Bezeichnung
    PIDD (PIDD Produkte)
    Synonyme
    1200011D09Rik antikoerper, AU042446 antikoerper, Pidd antikoerper, LRDD antikoerper, Lrdd antikoerper, p53 induced death domain protein 1 antikoerper, p53-induced death domain protein 1 antikoerper, Pidd1 antikoerper, PIDD1 antikoerper
    Hintergrund
    PIDD promotes apoptosis downstream of the tumor suppressor as component of the DNA damage/stress response pathway that connects p53/TP53 to apoptosis. It associates with NEMO/IKBKG and RIP1 and enhances sumoylation and ubiquitination of NEMO/IKBKG which is important for activation of the transcription factor NF-kappa-B. It associates with caspase-2 and RAIDD, and induces activation of caspase-2 which is an important regulator in the apoptotic pathways.
    UniProt
    Q9ERV7
    Pathways
    p53 Signalweg, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity
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