PIDD Antikörper (P53-Induced Death Domain Protein)

Details for Product anti-PIDD Antibody No. ABIN1169269
Antigen
Reaktivität
Maus
51
38
28
2
1
1
1
1
Wirt
Maus
53
5
Klonalität (Klon)
Monoklonal ()
Konjugat
Dieser PIDD Antikörper ist unkonjugiert
2
2
2
2
2
2
2
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
37
20
13
10
6
4
3
2
1
Optionen
Immunogen Mouse PIDD (Death Domain).
Klon Lise-1
Isotyp IgG2b
Spezifität Recognizes mouse PIDD.
Kreuzreaktivität Maus
Reinigung Purified from concentrated hybridoma tissue culture supernatant.
Reinheit >95 % (SDS-PAGE)
Antigen
Andere Bezeichnung PIDD (PIDD Antibody Abstract)
Hintergrund PIDD promotes apoptosis downstream of the tumor suppressor as component of the DNA damage/stress response pathway that connects p53/TP53 to apoptosis. It associates with NEMO/IKBKG and RIP1 and enhances sumoylation and ubiquitination of NEMO/IKBKG which is important for activation of the transcription factor NF-kappa-B. It associates with caspase-2 and RAIDD, and induces activation of caspase-2 which is an important regulator in the apoptotic pathways.
UniProt Q9ERV7
Pathways p53 Signalweg, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity
Applikations-hinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer In PBS containing 10 % glycerol and 0.02 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C,-20 °C
Informationen zur Lagerung Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.
Haltbarkeit 12 months