PIDD Antikörper
Kurzübersicht für PIDD Antikörper (ABIN1169269)
Target
Alle PIDD Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- Recognizes mouse PIDD.
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Kreuzreaktivität
- Maus
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Aufreinigung
- Purified from concentrated hybridoma tissue culture supernatant.
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Reinheit
- >95 % (SDS-PAGE)
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Immunogen
- Mouse PIDD (Death Domain).
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Isotyp
- IgG2b
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- In PBS containing 10 % glycerol and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. -
Haltbarkeit
- 12 months
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- PIDD (P53-Induced Death Domain Protein (PIDD))
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Andere Bezeichnung
- PIDD
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Hintergrund
- PIDD promotes apoptosis downstream of the tumor suppressor as component of the DNA damage/stress response pathway that connects p53/TP53 to apoptosis. It associates with NEMO/IKBKG and RIP1 and enhances sumoylation and ubiquitination of NEMO/IKBKG which is important for activation of the transcription factor NF-kappa-B. It associates with caspase-2 and RAIDD, and induces activation of caspase-2 which is an important regulator in the apoptotic pathways.
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UniProt
- Q9ERV7
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Pathways
- p53 Signalweg, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity
Target
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