CD247 Antikörper

Produktnummer ABIN161386

Produktdetails anti-CD247 Antikörper

Target: CD247 (CD247 Molecule (CD247))

Reaktivität: Maus

Wirt: Hamster

Klonalität: Monoklonal

Konjugat: Dieser CD247 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Spezifität: Mouse CD3z (zeta chain) also known as CD247

Aufreinigung: Purified

Immunogen: KLH conjugated mouse zeta-chain (CD3) sequence 151-164 . Donor: Armenian hamster

Klon: H146-968

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: This clone (H146-968) has been reported to work in flow cytometry (in permeabilized cells), Western Blotting and ELISA.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/ml

Lagerung: 4 °C

Details zu CD247

Target: CD247 (CD247 Molecule (CD247))

Andere Bezeichnung: CD3z (CD247 Produkte)

Synonyme: CD3-ZETA antikoerper, CD3H antikoerper, CD3Q antikoerper, CD3Z antikoerper, T3Z antikoerper, TCRZ antikoerper, 4930549J05Rik antikoerper, A430104F18Rik antikoerper, AW552088 antikoerper, Cd3 antikoerper, Cd3-eta antikoerper, Cd3-zeta antikoerper, Cd3h antikoerper, Cd3z antikoerper, Cd3zeta antikoerper, T3z antikoerper, Tcrk antikoerper, Tcrz antikoerper, LOC100136514 antikoerper, LOC100136549 antikoerper, LOC100305023 antikoerper, CD247 antikoerper, TCRzeta antikoerper, CD247 molecule antikoerper, CD247 antigen antikoerper, CD3zeta-2 antikoerper, CD3zeta-1 antikoerper, Cd247 molecule antikoerper, CD247 antikoerper, Cd247 antikoerper, cd3z antikoerper, cd247 antikoerper

Hintergrund: Purified Anti-Mouse CD3z Monoclonal Antibody detects the zeta subunit of the T cell receptor (TCR). The TCR complex consists of a ligand specific alpha/beta heterodimer non-covalently associated with five invariant chains including the CD3 gamma, delta, eta and zeta subunits. This complex regulates assembly and expression of the receptor and is thought to be responsible for transmembrane transduction of signals after binding to TCR Studies have suggested that the CD3z subunit (also know as CD247) plays an important role in two distinct cellular compartments. In the cytoplasm, it may function to regulate Ag receptor expression and in the plasma membrane it may be required for optimal signaling by the physiologic ligand Ag/MHC. The CD3z subunit is also associated with the CD16 IgG Fc receptor on NK cells. This clone (H146-968) has been reported to work in flow cytometry (in permeabilized cells), Western Blotting and ELISA.

Pathways: T-Zell Rezeptor Signalweg, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway