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CD247 Antikörper (pTyr142)

CD247 Reaktivität: Human, Maus WB, FACS Wirt: Maus Monoclonal EM-54 unconjugated
Produktnummer ABIN2749058
  • Target Alle CD247 Antikörper anzeigen
    CD247 (CD247 Molecule (CD247))
    Bindungsspezifität
    • 16
    • 14
    • 8
    • 8
    • 7
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr142
    Reaktivität
    • 101
    • 47
    • 21
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 75
    • 24
    • 6
    • 1
    Maus
    Klonalität
    • 73
    • 33
    Monoklonal
    Konjugat
    • 60
    • 10
    • 8
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    Dieser CD247 Antikörper ist unkonjugiert
    Applikation
    • 77
    • 53
    • 35
    • 14
    • 14
    • 11
    • 7
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    Spezifität
    The mouse monoclonal antibody EM-54 recognizes phosphorylated intracellular tyrosine 142 of CD3 zeta chain (CD247), which is a component of TCR/CD3 complex expressed on T cells.
    Kreuzreaktivität (Details)
    Human, Mouse
    Aufreinigung
    Purified by protein-A affinity chromatography.
    Reinheit
    > 95 % (by SDS-PAGE)
    Immunogen
    CP1 (pTyr142) - KLH
    Klon
    EM-54
    Isotyp
    IgG1
    Top Product
    Discover our top product CD247 Primärantikörper
  • Applikationshinweise
    Flow cytometry: Recommended dilution: 1-4 μg/mL. Intracellular staining.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Do not freeze.
  • Target
    CD247 (CD247 Molecule (CD247))
    Andere Bezeichnung
    CD3 zeta (CD247 Produkte)
    Synonyme
    CD3-ZETA antikoerper, CD3H antikoerper, CD3Q antikoerper, CD3Z antikoerper, T3Z antikoerper, TCRZ antikoerper, 4930549J05Rik antikoerper, A430104F18Rik antikoerper, AW552088 antikoerper, Cd3 antikoerper, Cd3-eta antikoerper, Cd3-zeta antikoerper, Cd3h antikoerper, Cd3z antikoerper, Cd3zeta antikoerper, T3z antikoerper, Tcrk antikoerper, Tcrz antikoerper, LOC100136514 antikoerper, LOC100136549 antikoerper, LOC100305023 antikoerper, CD247 antikoerper, TCRzeta antikoerper, CD247 molecule antikoerper, CD247 antigen antikoerper, CD3zeta-2 antikoerper, CD3zeta-1 antikoerper, Cd247 molecule antikoerper, CD247 antikoerper, Cd247 antikoerper, cd3z antikoerper, cd247 antikoerper
    Hintergrund
    CD247 Molecule,CD3 complex is crucial in transducing antigen-recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR complex. T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta (CD247). These CD3 subunits are structurally related members of the immunoglobulins super family encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules. This association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation.,CD3 zeta chain, CD247, T3Z, TCRz, IMD25
    Gen-ID
    919
    UniProt
    P20963
    Pathways
    T-Zell Rezeptor Signalweg, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
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