VEGFR2/CD309 Antikörper
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- Target Alle VEGFR2/CD309 (VEGFR2) Antikörper anzeigen
- VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser VEGFR2/CD309 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunoprecipitation (IP)
- Spezifität
- Recombinant human KDR (D1-7)
- Produktmerkmale
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Chromosomal location: 4q11-q12
Produced from sera of rabbits immunised with highly pure recombinant human soluble extracellular domain of KDR (110 kDa) as the immunizing antigen. - Aufreinigung
- Anti-human VEGFR-2/KDR was purified by affinity chromatography with immobilized protein A. The antibody is identical with the former described antibody r212 (see Lit.)
- Isotyp
- IgG
- Top Product
- Discover our top product VEGFR2 Primärantikörper
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- Applikationshinweise
- Western Blot: use 1-5 µg/mL
- Kommentare
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Rabbit IG Polyclonal Antibody
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.
- Buffer
- PBS
- Handhabung
- Centrifuge vial prior to opening.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- The lyophilized antibody is stable at room temperature for up to 1 month. The reconstituted antibody is stable for at least two weeks at 2-8 °C. Frozen aliquots are stable for at least 6 months when stored at -20 °C.
- Haltbarkeit
- 6 months
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- Target
- VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))
- Andere Bezeichnung
- VEGFR-2/KDR (VEGFR2 Produkte)
- Synonyme
- CD309 antikoerper, FLK1 antikoerper, VEGFR antikoerper, VEGFR2 antikoerper, 6130401C07 antikoerper, Flk-1 antikoerper, Flk1 antikoerper, Krd-1 antikoerper, Ly73 antikoerper, VEGFR-2 antikoerper, sVEGFR-2 antikoerper, Vegfr-2 antikoerper, FLK-1 antikoerper, flk-1 antikoerper, vegfr-2 antikoerper, KDR antikoerper, FLK/KDR antikoerper, flk1 antikoerper, flk1b antikoerper, kdrb antikoerper, si:busm1-205d10.1 antikoerper, si:ch211-254j6.1 antikoerper, si:ch211-278f21.4 antikoerper, wu:fc31a09 antikoerper, fk52c05 antikoerper, flk antikoerper, kdr antikoerper, kdra antikoerper, vegfr2 antikoerper, vegfr4 antikoerper, vegr2 antikoerper, wu:fk52c05 antikoerper, kinase insert domain receptor antikoerper, kinase insert domain protein receptor antikoerper, vascular endothelial growth factor receptor kdr-like antikoerper, kinase insert domain receptor (a type III receptor tyrosine kinase) antikoerper, kinase insert domain receptor like antikoerper, KDR antikoerper, Kdr antikoerper, LOC100136647 antikoerper, kdr antikoerper, kdrl antikoerper
- Hintergrund
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VEGF R1 (Flt-1), VEGF R2 (KDR/Flk-1), and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoietic development. Human VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis.
Synonyms: vascular endothelial growth factor receptor-2 , KDR, FLK1, CD309, VEGF receptor 2, VEGFR2, kinase insert domain protein receptor - NCBI Accession
- NP_002244, NM_002253
- UniProt
- P35968
- Pathways
- RTK Signalweg, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling
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