This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This CRADD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-98 amino acids from the Central region of human CRADD.
cradd antikoerper, MGC89035 antikoerper, zgc:101717 antikoerper, CRADD antikoerper, DKFZp468A2219 antikoerper, LOC100226369 antikoerper, raidd antikoerper, MGC78788 antikoerper, MRT34 antikoerper, RAIDD antikoerper, CASP2 and RIPK1 domain containing adaptor with death domain antikoerper, CASP2 and RIPK1 domain containing adaptor with death, gene 1 antikoerper, CASP2 and RIPK1 domain containing adaptor with death, gene 2 S homeolog antikoerper, CRADD antikoerper, cradd.1 antikoerper, cradd antikoerper, cradd.2.S antikoerper, Cradd antikoerper
Hintergrund
The protein encoded by this gene is a death domain (CARD/DD)-containing protein and has been shown to induce cell apoptosis. Through its CARD domain, this protein interacts with, and thus recruits, caspase 2/ICH1 to the cell death signal transduction complex that includes tumor necrosis factor receptor 1 (TNFR1A), RIPK1/RIP kinase, and numbers of other CARD domain-containing proteins.