CRADD Antikörper (AA 1-199)

Produktnummer ABIN3021483

Produktdetails anti-CRADD Antikörper

Target: CRADD (CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD))

Bindungsspezifität: AA 1-199

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CRADD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MEARDKQVLR SLRLELGAEV LVEGLVLQYL YQEGILTENH IQEINAQTTG LRKTMLLLDI LPSRGPKAFD TFLDSLQEFP WVREKLKKAR EEAMTDLPAG DRLTGIPSHI LNSSPSDRQI NQLAQRLGPE WEPMVLSLGL SQTDIYRCKA NHPHNVQSQV VEAFIRWRQR FGKQATFQSL HNGLRAVEVD PSLLLHMLE

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-199 of human RAIDD/RAIDD/CRADD (NP_003796.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CRADD

Target: CRADD (CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD))

Andere Bezeichnung: CRADD (CRADD Produkte)

Synonyme: cradd antikoerper, MGC89035 antikoerper, zgc:101717 antikoerper, CRADD antikoerper, DKFZp468A2219 antikoerper, LOC100226369 antikoerper, raidd antikoerper, MGC78788 antikoerper, MRT34 antikoerper, RAIDD antikoerper, CASP2 and RIPK1 domain containing adaptor with death domain antikoerper, CASP2 and RIPK1 domain containing adaptor with death, gene 1 antikoerper, CASP2 and RIPK1 domain containing adaptor with death, gene 2 S homeolog antikoerper, CRADD antikoerper, cradd.1 antikoerper, cradd antikoerper, cradd.2.S antikoerper, Cradd antikoerper

Hintergrund: This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with mental retardation. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants.,CRADD,MRT34,RAIDD,Cancer,Invasion and Metastasis,Cell Biology & Developmental Biology,Apoptosis,Mitochondrial Control of Apoptosis,Death Receptor Signaling Pathway,CRADD

Molekulargewicht: 11 kDa/22 kDa

Gen-ID: 8738

UniProt: P78560

Pathways: Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity