PERK Antikörper (pThr981)

Produktnummer ABIN1532072

Produktdetails anti-PERK Antikörper

Target: PERK (EIF2AK3) (Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 (EIF2AK3))

Bindungsspezifität: AA 947-996, pThr981

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PERK Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Spezifität:

PEK/PERK (Phospho-Thr981) Antibody detects endogenous levels of PEK/PERK only when phosphorylated at Thr981.

PhosphorylationH:T981 M:T980 R:T974

Aufreinigung: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human PEK/PERK around the phosphorylation site of Thr981.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC: 1:50~1:100 ELISA: 1:40000

Kommentare:

Unigene-Number: Hs.591589 (NCBI Gene Symbol: EIF2AK3)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable at -20°C for at least 1 year.

Haltbarkeit: 12 months

Details zu PERK

Target: PERK (EIF2AK3) (Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 (EIF2AK3))

Andere Bezeichnung: PEK/PERK (EIF2AK3 Produkte)

Synonyme: EIF2AK3 antikoerper, AI427929 antikoerper, Pek antikoerper, Perk antikoerper, PEK antikoerper, PERK antikoerper, WRS antikoerper, eukaryotic translation initiation factor 2 alpha kinase 3 antikoerper, EIF2AK3 antikoerper, Eif2ak3 antikoerper

Hintergrund:

Synonyms: PRKR-like endoplasmic reticulum kinase, Pancreatic eIF2-alpha kinase, HsPEK

NCBI Gene Symbol: EIF2AK3

Molekulargewicht: 125 kDa

Gen-ID: 9451

OMIM: 226980

UniProt: Q9NZJ5

Pathways: Hormone Transport, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Unfolded Protein Response