IKK alpha Antikörper (pSer176)
Kurzübersicht für IKK alpha Antikörper (pSer176) (ABIN1531285)
Target
Alle IKK alpha (CHUK) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
 - AA 151-200, pSer176
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Spezifität
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IKK-alpha (Phospho-Ser176) /IKK-beta (Phospho-Ser177) Antibody detects endogenous levels of IKK-alpha only when phosphorylated at Ser177.
PhosphorylationH:S176/S177 M:S176/S177 R:S176/S177
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Aufreinigung
 - The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
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Reinheit
 - > 95 %
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Immunogen
 - The antiserum was produced against synthesized peptide derived from human IKK-alpha around the phosphorylation site of Ser177.
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Isotyp
 - IgG
 
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Applikationshinweise
 - WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:1000
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Kommentare
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Unigene-Number: Hs.198998, Hs.656458 (NCBI Gene Symbol: CHUK)
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Beschränkungen
 - Nur für Forschungszwecke einsetzbar
 
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Format
 - Liquid
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Konzentration
 - 1 mg/mL
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Buffer
 - phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
 - Sodium azide
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Vorsichtsmaßnahmen
 - This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
 - -20 °C
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Informationen zur Lagerung
 - Stable at -20°C for at least 1 year.
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Haltbarkeit
 - 12 months
 
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- IKK alpha (CHUK) (conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))
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Andere Bezeichnung
 - IKK-alpha
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Hintergrund
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Synonyms: CHUK, Conserved helix-loop-helix ubiquitous kinase, I kappa-B kinase alpha, I-kappa-B kinase 1, IkappaB kinase, IkBKA, IKK-A, IKK-alpha, IKK1, IKKA, Inhibitor of nuclear factor kappa-B kinase alpha subunit, kinase IKK-alpha, NFKBIKA, Nuclear factor NFkapp
NCBI Gene Symbol: CHUK
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Molekulargewicht
 - 84 kDa
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Gen-ID
 - 1147, 3551
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OMIM
 - 600664
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UniProt
 - O15111, O14920
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Pathways
 - PI3K-Akt Signalweg, NF-kappaB Signalweg, RTK Signalweg, T-Zell Rezeptor Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteine
 
Target
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