AKAP5 Antikörper (Middle Region)

Produktnummer ABIN1449866

Produktdetails anti-AKAP5 Antikörper

Target: AKAP5 (A Kinase (PRKA) Anchor Protein 5 (AKAP5))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AKAP5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KQFLISAENE QVGVFANDNG FEDRTSEQYE TLLIETASSL VKNAIQLSIE

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Dog, BovineSpecies reactivity (tested):Human

Aufreinigung: Purified using peptide immunoaffinity column

Immunogen: Synthetic peptide directed towards the middle region of human AKAP5

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Details zu AKAP5

Target: AKAP5 (A Kinase (PRKA) Anchor Protein 5 (AKAP5))

Andere Bezeichnung: AKAP5 (AKAP5 Produkte)

Synonyme: AKAP5 antikoerper, AKAP75 antikoerper, AKAP79 antikoerper, H21 antikoerper, AKAP antikoerper, P75 antikoerper, 3526401B18Rik antikoerper, AKAP 150 antikoerper, AKAP-5 antikoerper, AKAP150 antikoerper, BB098886 antikoerper, Gm258 antikoerper, P150 antikoerper, Akap79 antikoerper, A kinase (PRKA) anchor protein 5 antikoerper, A-kinase anchoring protein 5 antikoerper, AKAP5 antikoerper, Akap5 antikoerper

Substanzklasse: Viral Protein

Hintergrund: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. AKAP5 is a member of the AKAP family. It binds to the RII-beta regulatory subunit of PKA, and also to protein kinase C and the phosphatase calcineurin. It is predominantly expressed in cerebral cortex and may anchor the PKA protein at postsynaptic densities (PSD) and be involved in the regulation of postsynaptic events. It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT.The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to the RII-beta regulatory subunit of PKA, and also to protein kinase C and the phosphatase calcineurin. It is predominantly expressed in cerebral cortex and may anchor the PKA protein at postsynaptic densities (PSD) and be involved in the regulation of postsynaptic events. It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT.Synonyms: A-kinase anchor protein 5, A-kinase anchor protein 79 kDa, AKAP79, cAMP-dependent protein kinase regulatory subunit II high affinity-binding protein

Gen-ID: 9495

NCBI Accession: NP_004848

Pathways: cAMP Metabolic Process