MYBPC3 Antikörper (Alexa Fluor 350)

Produktnummer ABIN1405131

Produktdetails anti-MYBPC3 Antikörper (Alexa Fluor 350)

Target: MYBPC3 (Myosin Binding Protein C, Cardiac (MYBPC3))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYBPC3 Antikörper ist konjugiert mit Alexa Fluor 350

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MYBPC3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu MYBPC3

Target: MYBPC3 (Myosin Binding Protein C, Cardiac (MYBPC3))

Andere Bezeichnung: MYBPC3 (MYBPC3 Produkte)

Synonyme: MGC114614 antikoerper, hm:zehn0716 antikoerper, im:6900815 antikoerper, zgc:152717 antikoerper, zgc:158442 antikoerper, fhc antikoerper, cmh4 antikoerper, mybp-c antikoerper, CMH4 antikoerper, FHC antikoerper, MYBP-C antikoerper, myosin binding protein C, cardiac S homeolog antikoerper, myosin binding protein C, cardiac antikoerper, mybpc3.S antikoerper, MYBPC3 antikoerper, mybpc3 antikoerper, Mybpc3 antikoerper

Hintergrund:

Synonyms: C protein cardiac muscle isoform, cardiac muscle isoform, cardiac-type, C-protein, Cardiac MyBP C, Cardiac MyBP-C, Cardiac myosin binding protein C, MYBP C, MYBPC, MYBPC3, Myosin binding protein C cardiac, Myosin binding protein C cardiac-type, Myosin-binding protein C, MYPC3_HUMAN.

Background: MYBPC3 encodes the cardiac isoform of the thick-filament myosin-binding protein C. It is found in the crossbridge-bearing zone (C region) of A bands in vertebrate striated muscle. Regulatory phosphorylation of MYBPC3 by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. MYBPC3 binds F-Actin, MHC and native thin filaments, and modifies the activity of Actin-activated myosin ATPase. Mutations in the MYBPC3 gene lead mainly to truncation of the protein, which results in one cause of familial hypertrophic cardiomyopathy type 4 (CMH4), a heart disorder characterized by ventricular hypertrophy, which often involves the interventricular septum and is usually asymmetric. The MYBPC3 gene maps to chromosome 11p11.2.

Gen-ID: 4607