MYBPC3 Antikörper (AA 1070-1123)

Produktnummer ABIN5693035

Produktdetails anti-MYBPC3 Antikörper

Target: MYBPC3 (Myosin Binding Protein C, Cardiac (MYBPC3))

Bindungsspezifität: AA 1070-1123

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYBPC3 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Marke: Picoband™

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for MYBPC3 detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.

Immunogen: E. coli-derived human MYBPC3 recombinant protein (Position: Q1070-H1123).

Anwendungsinformationen

Applikationshinweise:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).

Application Details: Western blot, 0.1-0.5 μg/mL
Immunohistochemistry(Paraffin-embedded Section), 0.5-1 μg/mL
Direct ELISA, 0.1-0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Referenzen für anti-MYBPC3 Antikörper (ABIN5693035)

Qian, Gong, Yang, Chen, Chen, Xu, Wu, Tang, Gao, Zeng: "Diastolic dysfunction in spontaneous type 2 diabetes rhesus monkeys: a study using echocardiography and magnetic resonance imaging." in: BMC cardiovascular disorders, Vol. 15, pp. 59, (2015) (PubMed).

Details zu MYBPC3

Target: MYBPC3 (Myosin Binding Protein C, Cardiac (MYBPC3))

Andere Bezeichnung: MYBPC3 (MYBPC3 Produkte)

Synonyme: MGC114614 antikoerper, hm:zehn0716 antikoerper, im:6900815 antikoerper, zgc:152717 antikoerper, zgc:158442 antikoerper, fhc antikoerper, cmh4 antikoerper, mybp-c antikoerper, CMH4 antikoerper, FHC antikoerper, MYBP-C antikoerper, myosin binding protein C, cardiac S homeolog antikoerper, myosin binding protein C, cardiac antikoerper, mybpc3.S antikoerper, MYBPC3 antikoerper, mybpc3 antikoerper, Mybpc3 antikoerper

Hintergrund:

Synonyms: Myosin-binding protein C, cardiac-type, Cardiac MyBP-C, C-protein, cardiac muscle isoform, MYBPC3

Background: The myosin-binding protein C, cardiac-type is a protein that in humans is encode by the MYBPC3 gene. MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy.

UniProt: Q14896