MYBPC3 Antikörper (AA 200-400)
Kurzübersicht für MYBPC3 Antikörper (AA 200-400) (ABIN6144221)
Target
Alle MYBPC3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 200-400
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Sequenz
- SSKVGQHLQL HDSYDRASKV YLFELHITDA QPAFTGSYRC EVSTKDKFDC SNFNLTVHEA MGTGDLDLLS AFRRTSLAGG GRRISDSHED TGILDFSSLL KKRDSFRTPR DSKLEAPAEE DVWEILRQAP PSEYERIAFQ YGVTDLRGML KRLKGMRRDE KKSTAFQKKL EPAYQVSKGH KIRLTVELAD HDAEVKWLKN G
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Kreuzreaktivität
- Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 200-400 of human MYBPC3 (NP_000247.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- MYBPC3 (Myosin Binding Protein C, Cardiac (MYBPC3))
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Andere Bezeichnung
- MYBPC3
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Hintergrund
- MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy.,MYBPC3,CMD1MM,CMH4,FHC,LVNC10,MYBP-C,cardiac,Cell Biology & Developmental Biology,Cytoskeleton,Actins,Cardiovascular,Heart,Contractility,Hypertrophy,MYBPC3
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Molekulargewicht
- 140 kDa
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Gen-ID
- 4607
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UniProt
- Q14896
Target
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