KCNAB1 Antikörper (AA 131-230) (Alexa Fluor 350)

Produktnummer ABIN1400199

Produktdetails anti-KCNAB1 Antikörper (Alexa Fluor 350)

Target: KCNAB1 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, beta Member 1 (KCNAB1))

Bindungsspezifität: AA 131-230

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCNAB1 Antikörper ist konjugiert mit Alexa Fluor 350

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Ratte

Homologie: Mouse,Dog,Cow,Sheep,Pig,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KCNAB1/Kv beta 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu KCNAB1

Target: KCNAB1 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, beta Member 1 (KCNAB1))

Andere Bezeichnung: KCNAB1 (KCNAB1 Produkte)

Synonyme: KCNAB1 antikoerper, zgc:113627 antikoerper, AKR6A3 antikoerper, KCNA1B antikoerper, KV-BETA-1 antikoerper, Kvb1.3 antikoerper, hKvBeta3 antikoerper, hKvb3 antikoerper, Kvbeta1.1 antikoerper, KVBETA1 antikoerper, Kv-beta-1 antikoerper, Akr8a8 antikoerper, mKv(beta)1 antikoerper, KvBeta3 antikoerper, potassium voltage-gated channel subfamily A member regulatory beta subunit 1 antikoerper, potassium voltage-gated channel, shaker-related subfamily, beta member 1 a antikoerper, potassium voltage-gated channel, shaker-related subfamily, beta member 1 antikoerper, KCNAB1 antikoerper, kcnab1a antikoerper, Kcnab1 antikoerper

Hintergrund:

Synonyms: hKvb3; hKvBeta3; K+ channel subunit beta-1; KCAB1_HUMAN; KCNA1B; KCNAB1; KV-BETA-1; Kvb1.3; Voltage-gated potassium channel beta-1 subunit; Voltage-gated potassium channel subunit beta-1.

Background: Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles and other excitable cells. The KV gene family encodes more than 30 proteins that comprise the subunits of the K+ channels, and they vary in their gating and permeation properties, subcellular distribution and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming å subunits (KV), which include the KV1, KV2, KV3 and KV4 proteins, and accessory or KV-subunits that modify the gating properties of the coexpressed KV subunits. KV, also known as KCNAB1 (potassium voltage-gated channel, shaker-related subfamily, beta member 1), is a 419 amino acid accessory K+ channel protein that exists as three alternatively spliced isoforms and regulates the activity of the pore-forming å subunit. It is expressed in brain, with highest levels detected in caudate nucleus, hippocampus and thalamus.

Gen-ID: 7881