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KCNAB1 Antikörper (N-Term)

KCNAB1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB40526 unconjugated
Produktnummer ABIN1881473
  • Target Alle KCNAB1 Antikörper anzeigen
    KCNAB1 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, beta Member 1 (KCNAB1))
    Bindungsspezifität
    • 15
    • 7
    • 7
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    AA 15-44, N-Term
    Reaktivität
    • 41
    • 20
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 40
    • 2
    Kaninchen
    Klonalität
    • 40
    • 2
    Polyklonal
    Konjugat
    • 14
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KCNAB1 Antikörper ist unkonjugiert
    Applikation
    • 37
    • 22
    • 13
    • 13
    • 6
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This KCNAB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-44 amino acids from the N-terminal region of human KCNAB1.
    Klon
    RB40526
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product KCNAB1 Primärantikörper
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Decher, Gonzalez, Streit, Sachse, Renigunta, Soom, Heinemann, Daut, Sanguinetti: "Structural determinants of Kvbeta1.3-induced channel inactivation: a hairpin modulated by PIP2." in: The EMBO journal, Vol. 27, Issue 23, pp. 3164-74, (2008) (PubMed).

    Cavalleri, Weale, Shianna, Singh, Lynch, Grinton, Szoeke, Murphy, Kinirons, ORourke, Ge, Depondt, Claeys, Pandolfo, Gumbs, Walley, McNamara, Mulley, Linney, Sheffield, Radtke, Tate, Chissoe et al.: "Multicentre search for genetic susceptibility loci in sporadic epilepsy syndrome and seizure types: a case-control study...." in: Lancet neurology, Vol. 6, Issue 11, pp. 970-80, (2007) (PubMed).

    Lamesch, Li, Milstein, Fan, Hao, Szabo, Hu, Venkatesan, Bethel, Martin, Rogers, Lawlor, McLaren, Dricot, Borick, Cusick, Vandenhaute, Dunham, Hill, Vidal: "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." in: Genomics, Vol. 89, Issue 3, pp. 307-15, (2007) (PubMed).

    Hanna, Kruskal, Ezekowitz, Bloom, Collier: "Role of macrophage oxidative burst in the action of anthrax lethal toxin." in: Molecular medicine (Cambridge, Mass.), Vol. 1, Issue 1, pp. 7-18, (1996) (PubMed).

  • Target
    KCNAB1 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, beta Member 1 (KCNAB1))
    Andere Bezeichnung
    KCNAB1 (KCNAB1 Produkte)
    Synonyme
    KCNAB1 antikoerper, zgc:113627 antikoerper, AKR6A3 antikoerper, KCNA1B antikoerper, KV-BETA-1 antikoerper, Kvb1.3 antikoerper, hKvBeta3 antikoerper, hKvb3 antikoerper, Kvbeta1.1 antikoerper, KVBETA1 antikoerper, Kv-beta-1 antikoerper, Akr8a8 antikoerper, mKv(beta)1 antikoerper, KvBeta3 antikoerper, potassium voltage-gated channel subfamily A member regulatory beta subunit 1 antikoerper, potassium voltage-gated channel, shaker-related subfamily, beta member 1 a antikoerper, potassium voltage-gated channel, shaker-related subfamily, beta member 1 antikoerper, KCNAB1 antikoerper, kcnab1a antikoerper, Kcnab1 antikoerper
    Hintergrund
    Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member includes three distinct isoforms which are encoded by three alternatively spliced transcript variants of this gene. These three isoforms are beta subunits, which form heteromultimeric complex with alpha subunits and modulate the activity of the pore-forming alpha subunits.
    Molekulargewicht
    46563
    NCBI Accession
    NP_003462, NP_751891, NP_751892
    UniProt
    Q14722
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