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STIM1 Antikörper (AA 85-180) (Alexa Fluor 647)

STIM1 Reaktivität: Ratte IF (cc), IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 647
Produktnummer ABIN1399560
  • Target Alle STIM1 Antikörper anzeigen
    STIM1 (Stromal Interaction Molecule 1 (STIM1))
    Bindungsspezifität
    • 16
    • 15
    • 14
    • 6
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 85-180
    Reaktivität
    • 77
    • 57
    • 28
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Ratte
    Wirt
    • 79
    • 10
    • 1
    • 1
    Kaninchen
    Klonalität
    • 71
    • 20
    Polyklonal
    Konjugat
    • 44
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser STIM1 Antikörper ist konjugiert mit Alexa Fluor 647
    Applikation
    • 48
    • 31
    • 26
    • 25
    • 25
    • 20
    • 12
    • 12
    • 9
    • 6
    • 3
    • 3
    • 2
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Spezifität
    May cross react with STIM2
    Kreuzreaktivität
    Ratte
    Homologie
    Human,Mouse,Dog,Cow,Pig,Horse,Chicken,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human STIM1
    Isotyp
    IgG
    Top Product
    Discover our top product STIM1 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    STIM1 (Stromal Interaction Molecule 1 (STIM1))
    Andere Bezeichnung
    STIM1 (STIM1 Produkte)
    Synonyme
    stim1 antikoerper, MGC76045 antikoerper, STIM1 antikoerper, si:dkey-24p1.5 antikoerper, MGC154748 antikoerper, si:ch211-112l17.2 antikoerper, Stim1 antikoerper, D11S4896E antikoerper, GOK antikoerper, TAM antikoerper, SIM antikoerper, stromal interaction molecule 1 antikoerper, stromal interaction molecule 1a antikoerper, stromal interaction molecule 1 L homeolog antikoerper, stromal interaction molecule 1b antikoerper, STIM1 antikoerper, stim1 antikoerper, stim1a antikoerper, stim1.L antikoerper, stim1b antikoerper, Stim1 antikoerper
    Hintergrund

    Synonyms: GOK, TAM, TAM1, IMD10, STRMK, D11S4896E, Stromal interaction molecule 1, STIM1

    Background: Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit, TMEM142A/ORAI1.

    Gen-ID
    6786
    UniProt
    Q13586
    Pathways
    T-Zell Rezeptor Signalweg, BCR Signaling
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