Acetyl-CoA Carboxylase alpha Antikörper (Alexa Fluor 555)

Produktnummer ABIN1394057

Produktdetails anti-Acetyl-CoA Carboxylase alpha Antikörper (Alexa Fluor 555)

Target: Acetyl-CoA Carboxylase alpha (ACACA)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Acetyl-CoA Carboxylase alpha Antikörper ist konjugiert mit Alexa Fluor 555

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ACACA

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P)(1:50-200)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Acetyl-CoA Carboxylase alpha

Target: Acetyl-CoA Carboxylase alpha (ACACA)

Andere Bezeichnung: Acaca (ACACA Produkte)

Synonyme: ACAC antikoerper, ACACAD antikoerper, ACC antikoerper, ACC1 antikoerper, ACCA antikoerper, A530025K05Rik antikoerper, Acac antikoerper, Acc1 antikoerper, Gm738 antikoerper, AT-ACC1 antikoerper, EMB22 antikoerper, EMBRYO DEFECTIVE 22 antikoerper, GK antikoerper, GURKE antikoerper, PAS3 antikoerper, PASTICCINO 3 antikoerper, acetyl-CoA carboxylase 1 antikoerper, acc antikoerper, fj43d01 antikoerper, im:7138837 antikoerper, si:ch211-199d18.1 antikoerper, wu:fj43d01 antikoerper, acetyl-CoA carboxylase alpha antikoerper, acetyl-Coenzyme A carboxylase alpha antikoerper, acetyl-CoA carboxylase 1 antikoerper, ACACA antikoerper, Acaca antikoerper, ACC1 antikoerper, acaca antikoerper

Hintergrund:

Synonyms: ACAC, ACACA, ACACA, ACACA_HUMAN, ACC alpha, ACC-alpha, ACC1, ACC1, ACCA, Acetyl Coenzyme A, Biotin carboxylase, ACACA_MOUSE, Acetyl Coenzyme A carboxylase alpha, ACACA_RAT.

Background: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. Exercise diminishes the activity of acetyl-CoA carboxylase in human muscle. ACC alpha (ACC1) is the rate-limiting enzyme in the biogenesis of long-chain fatty acids, and ACCâ^ (ACC2) may control mitochondrial fatty acid oxidation. These two isoforms of ACC control the amount of fatty acids in the cells. The catalytic function of ACC alpha is regulated by phosphorylation (inactive) and dephosphorylation (active) of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA, which serve as the enzyme’s short-term regulatory mechanism. The gene encoding ACC alpha maps to human chromosome 17 and encodes a form of ACC, which is the major ACC in lipogenic tissues. The catalytic core of ACCâ^ is homologous to that of the ACCå, except for an additional peptide of about 150 amino acids at the N-terminus.

Pathways: AMPK Signaling, Ribonucleoside Biosynthetic Process, Warburg Effekt