Acetyl-CoA Carboxylase alpha Antikörper

Produktnummer ABIN7265369

Der Kaninchen Monoklonal anti-Acetyl-CoA Carboxylase alpha Antikörper wird verwendet zum Nachweis von Acetyl-CoA Carboxylase alpha in Proben von Human. Er wurde validiert für WB, IHC und IP.

Kurzübersicht für Acetyl-CoA Carboxylase alpha Antikörper (ABIN7265369)

Target: Acetyl-CoA Carboxylase alpha (ACACA)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Acetyl-CoA Carboxylase alpha Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Produktdetails anti-Acetyl-CoA Carboxylase alpha Antikörper

Verwendungszweck: ACC1 Rabbit mAb

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthesized peptide derived from human ACC1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IP,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Acetyl-CoA Carboxylase alpha

Target: Acetyl-CoA Carboxylase alpha (ACACA)

Andere Bezeichnung: ACC1

Hintergrund: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.,ACC, ACAC, ACC1, ACCA, ACACAD,Endocrine & Metabolism,Lipid Metabolism,AMPK Signaling Pathway,Warburg Effect,ACC1

Molekulargewicht: 257kDa/259kDa/265kDa/269kDa

Gen-ID: 31

UniProt: Q13085

Pathways: AMPK Signaling, Ribonucleoside Biosynthetic Process, Warburg Effekt