PPP2R2B Antikörper (AA 51-130)

Produktnummer ABIN1386570

Produktdetails anti-PPP2R2B Antikörper

Target: PPP2R2B (Protein Phosphatase 2, Regulatory Subunit B, beta (PPP2R2B))

Bindungsspezifität: AA 51-130

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPP2R2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Ratte

Homologie: Mouse,Dog,Sheep,Pig,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PPP2R2B/PP2A-B55

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu PPP2R2B

Target: PPP2R2B (Protein Phosphatase 2, Regulatory Subunit B, beta (PPP2R2B))

Andere Bezeichnung: PPP2R2B/PP2A-B55 (PPP2R2B Produkte)

Synonyme: B55BETA antikoerper, PP2AB55BETA antikoerper, PP2ABBETA antikoerper, PP2APR55B antikoerper, PP2APR55BETA antikoerper, PR2AB55BETA antikoerper, PR2ABBETA antikoerper, PR2APR55BETA antikoerper, PR52B antikoerper, PR55-BETA antikoerper, PR55BETA antikoerper, SCA12 antikoerper, Pppr2b2 antikoerper, 2900026H06Rik antikoerper, 6330404L05Rik antikoerper, E130009M08Rik antikoerper, PP2A-PR55B antikoerper, PP2A antikoerper, ppp2r2b-a antikoerper, ppp2r2c antikoerper, ppp2r2b antikoerper, zgc:101861 antikoerper, PPP2R2B antikoerper, protein phosphatase 2 regulatory subunit Bbeta antikoerper, protein phosphatase 2, regulatory subunit B, beta antikoerper, protein phosphatase 2 regulatory subunit B, beta L homeolog antikoerper, protein phosphatase 2 regulatory subunit B, beta antikoerper, protein phosphatase 2, regulatory subunit B, beta b antikoerper, PPP2R2B antikoerper, Ppp2r2b antikoerper, ppp2r2b.L antikoerper, ppp2r2b antikoerper, ppp2r2bb antikoerper

Hintergrund:

Synonyms: 2ABB_HUMAN; B55 beta; Beta isoform of regulatory subunit B55 protein phosphatase 2; MGC24888; PP2A B Subunit B Alpha Isoform; PP2A B55beta; PP2A PR55B; PP2A subunit B B beta isoform; PP2A subunit B B55 beta isoform; PP2A subunit B isoform B55 beta; PP2A subunit B isoform B55-beta; PP2A subunit B isoform beta; PP2A subunit B isoform PR55 beta; PP2A subunit B isoform PR55-beta; PP2A subunit B isoform R2 beta; PP2A subunit B isoform R2-beta; PP2A subunit B PR55 beta isoform; PP2A subunit B R2 beta isoform; Ppp2r2b; PR2AB beta; PR2AB55 beta; PR2APR55 beta; PR52B; PR55 beta; Protein phosphatase 2 formerly 2A regulatory subunit B PR 52 beta isoform; Protein phosphatase 2 formerly 2A regulatory subunit B beta isoform; Protein phosphatase 2 regulatory subunit B; Protein phosphatase 2 regulatory subunit B beta isoform; SCA 12; SCA12; Serine/threonine protein phosphatase 2A 55 kDa regulatory subunit B beta isoform; Serine/Threonine Protein Phosphatase 2A 56kDa Regulatory Subunit Alpha Isoform; Serine/threonine protein phosphatase 2A neuronal isoform; Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform.

Background: In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Four major families of protein phosphatase catalytic subunits have been identified, designated PP1, PP2A, PP2B (calcineurin) and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4) is a putative member of a novel PP family. The PP2A family comprises subfamily members PP2Aå and PP2A. The PP2A catalytic subunit associates with a variety of regulatory subunits. The B family of regulatory subunits (including B55, B56 and PR72/130 subfamilies) is believed to participate in substrate specificity and catalytic activity. PP2A-B55, also known as PP2A regulatory subunit subfamily B55 or PP2A-B1, is a B subfamily consisting of four B55 isoforms (Alpha,Beta, Gamma and Delta) encoded by four distinct genes.

Pathways: PI3K-Akt Signalweg, Mitotic G1-G1/S Phases, Hepatitis C