NPC2 Antikörper (AA 20-80)
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- Target Alle NPC2 Antikörper anzeigen
- NPC2 (Niemann-Pick Disease, Type C2 (NPC2))
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Bindungsspezifität
- AA 20-80
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Reaktivität
- Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser NPC2 Antikörper ist unkonjugiert
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Applikation
- ELISA, Western Blotting (WB)
- Kreuzreaktivität
- Maus
- Homologie
- Human,Rat,Cow,Sheep
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Niemann Pick C2
- Isotyp
- IgG
- Top Product
- Discover our top product NPC2 Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- NPC2 (Niemann-Pick Disease, Type C2 (NPC2))
- Andere Bezeichnung
- NPC2/Niemann Pick C2 (NPC2 Produkte)
- Synonyme
- 2700012J19Rik antikoerper, AA408070 antikoerper, AU045843 antikoerper, HE1 antikoerper, EDDM1 antikoerper, re1 antikoerper, CE1 antikoerper, EPI-1 antikoerper, cb292 antikoerper, sb:cb292 antikoerper, NPC intracellular cholesterol transporter 2 antikoerper, Niemann-Pick disease, type C2 antikoerper, Npc2 antikoerper, NPC2 antikoerper, npc2 antikoerper
- Hintergrund
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Synonyms: EDDM1, Epididymal protein 1, Epididymal secretory protein, Epididymal secretory protein E1, HE1, Human epididymis-specic protein 1, Niemann-Pick disease type C2, Niemann-Pick disease type C2 protein, NPC2, NPC2_HUMAN, Tissue specic secretory protein.
Background: NPC2 is a secreted protein mapping against gene 14q24.3 (1,2). NPC2 regulates the lipid composition of sperm membranes during maturation in the epididymis(1,2). Mutations in the NPC2 gene may cause Nieman-Pick type C2 disease and frontal lobe atrophy (1,2,3). Nieman-Pick type C2 is a fatal hereditary disease characterized by defective lysosome release of cholesterol (3). The disease is caused by HE1 deficiency, a lysosmal protein proven to be undetectable in fibroblasts from NPC2 patients (3). This differentiates NPC2 from NPC1, as NPC1 has HE1 protein present (3).
- Pathways
- SARS-CoV-2 Protein Interaktom
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