TNFRSF4 Antikörper (FITC)

Produktnummer ABIN118272

Produktdetails anti-TNFRSF4 Antikörper (FITC)

Target: TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser TNFRSF4 Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Spezifität: This antibody recognises OX40 (CD134), a cell surface antigen expressed only by activated T lymphocytes.

Aufreinigung: Affinity Chromatography on Protein G.

Immunogen: CHO cells transfected with murine OX40. Spleen cells from immunised AO rats were fused with cells of the mouse NS1 myeloma cell line.

Klon: OX-86

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: Use 10 μL of neat-1/10 diluted antibody to label 1x10^6 cells. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: PBS, pH 7.4 with 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu TNFRSF4

Target: TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))

Andere Bezeichnung: CD134 / TNFRSF4 (TNFRSF4 Produkte)

Synonyme: TNFRSF4 antikoerper, ACT35 antikoerper, CD134 antikoerper, Ly-70 antikoerper, Ox40 antikoerper, TXGP1L antikoerper, Txgp1 antikoerper, OX40 antikoerper, TNF receptor superfamily member 4 antikoerper, tumor necrosis factor receptor superfamily, member 4 antikoerper, TNFRSF4 antikoerper, Tnfrsf4 antikoerper

Hintergrund: The OX40 receptor is also known as CD134, ACT35, and tumour necrosis factor receptor superfamily member 4. This receptor is expressed on activated CD4+ and CD8+ T cells and B cells. The OX40 receptor binds to the OX40 ligand to provide a co-stimulatory signal that is independent of CD28. Blockade of OX40-OX40 ligand interactions has been shown to ameliorate experimental EAE and inflammatory bowel disease, imply that these interactions are important in the pathogenesis of some autoimmune diseases.Synonyms: ACT35 antigen, OX40L receptor, TAX transcriptionally-activated glycoprotein 1 receptor, TNFRSF4, TXGP1L, Tumor necrosis factor receptor superfamily member 4

Gen-ID: 22163

NCBI Accession: NP_035789

UniProt: P47741

Pathways: Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints