WIPF1 Antikörper (pSer488) (Alexa Fluor 647)

Produktnummer ABIN1177222

Produktdetails anti-WIPF1 Antikörper (Alexa Fluor 647)

Target: WIPF1 (WAS/WASL Interacting Protein Family, Member 1 (WIPF1))

Bindungsspezifität: pSer488

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser WIPF1 Antikörper ist konjugiert mit Alexa Fluor 647

Applikation: Intracellular Staining (ICS)

Marke: BD Phosflow™

Aufreinigung: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogen: Phosphorylated Human WIP Peptide

Klon: K32-824

Isotyp: IgG1 kappa

Anwendungsinformationen

Probenmenge: 20 μL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Aqueous buffered solution containing BSA and ≤0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The antibody was conjugated to Alexa Fluor® 647 under optimum conditions, and unreacted Alexa Fluor® 647 was removed.

Details zu WIPF1

Target: WIPF1 (WAS/WASL Interacting Protein Family, Member 1 (WIPF1))

Andere Bezeichnung: WIP (WIPF1 Produkte)

Synonyme: WASPIP antikoerper, PRPL-2 antikoerper, WIP antikoerper, AI115543 antikoerper, D2Ertd120e antikoerper, Waspip antikoerper, Wip antikoerper, WAS/WASL interacting protein family member 1 antikoerper, WAS/WASL interacting protein family, member 1 antikoerper, WIPF1 antikoerper, Wipf1 antikoerper

Hintergrund: Wiskott-Adrich syndrome protein (WASP)-Interacting Protein (WIP) is a member of the verprolin family of proteins that regulate cytoskeletal organization in a wide variety of cellular activities, including endocytosis, cellular adhesion and migration, mast cell degranulation, and lymphocyte activation. The 503-amino acid WIP protein contains binding sites for actin (globular and filamentous) and other proteins that are involved in the regulation of actin polymerization, such as WASP, N-WASP, profilin, cortactin, Hck, and NCK. As its functions imply, WIP is localized in actin-rich cell structures. The K32-824 monoclonal antibody recognizes the phosphorylated serine 488 (pS488) of human WIP. The orthologous phosphorylation sites in mouse and rat WIP are S478 and S472, respectively.
Synonyms: PRPL-2 protein, WAIP, WASIP, WASPIP

Pathways: RTK Signalweg