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TNFRSF10A Antikörper

TNFRSF10A Reaktivität: Human FACS, IP, ICC, Func Wirt: Maus Monoclonal HS101 unconjugated
Produktnummer ABIN1169236
  • Target Alle TNFRSF10A Antikörper anzeigen
    TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))
    Reaktivität
    • 88
    • 5
    • 3
    • 1
    • 1
    Human
    Wirt
    • 47
    • 41
    Maus
    Klonalität
    • 49
    • 39
    Monoklonal
    Konjugat
    • 48
    • 8
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TNFRSF10A Antikörper ist unkonjugiert
    Applikation
    • 44
    • 32
    • 25
    • 19
    • 17
    • 11
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC), Functional Studies (Func)
    Spezifität
    Recognizes human TRAIL-R1.
    Kreuzreaktivität
    Human
    Kreuzreaktivität (Details)
    Does not cross-react with human TRAIL-R2, -R3 or -R4.
    Aufreinigung
    Purified from concentrated hybridoma tissue culture supernatant.
    Reinheit
    >95 % (SDS-PAGE)
    Immunogen
    Recombinant human TRAIL-R1 (DR4).
    Klon
    HS101
    Isotyp
    IgG1
    Top Product
    Discover our top product TNFRSF10A Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    In PBS containing 10 % glycerol.
    Konservierungsmittel
    Without preservative
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.
    Haltbarkeit
    12 months
  • Target
    TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))
    Andere Bezeichnung
    TRAIL-R1 (TNFRSF10A Produkte)
    Synonyme
    APO2 antikoerper, CD261 antikoerper, DR4 antikoerper, TRAILR-1 antikoerper, TRAILR1 antikoerper, TNFRSF10A antikoerper, TNF receptor superfamily member 10a antikoerper, tumor necrosis factor receptor superfamily member 26 antikoerper, tumor necrosis factor receptor superfamily, member 10a antikoerper, TNFRSF10A antikoerper, LOC510798 antikoerper
    Hintergrund
    TRAIL-R1 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.
    UniProt
    O00220
    Pathways
    Apoptose, Positive Regulation of Endopeptidase Activity
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