TNFRSF10A Antikörper (Atto 488)
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- Target Alle TNFRSF10A Antikörper anzeigen
- TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser TNFRSF10A Antikörper ist konjugiert mit Atto 488
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Applikation
- Flow Cytometry (FACS), Immunocytochemistry (ICC)
- Spezifität
- Recognizes human TRAIL-R1.
- Kreuzreaktivität
- Human
- Kreuzreaktivität (Details)
- Does not cross-react with human TRAIL-R2, -R3 or -R4.
- Aufreinigung
- Purified from concentrated hybridoma tissue culture supernatant.
- Reinheit
- >95 % (SDS-PAGE)
- Immunogen
- Recombinant human TRAIL-R1 (DR4).
- Klon
- HS101
- Isotyp
- IgG1
- Top Product
- Discover our top product TNFRSF10A Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Kommentare
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New ATTO-fluorescent antibodies show increased photostability, outstanding brightness and intense signals. ATTO dyes are thermally stable, resistant to environmental changes and show no significant isomerization. ATTO 488 shows bright green fluorescence (lambdaabs (max): 501nm, lambdaem (max): 523nm, epsilonmax: 90'000).
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- In PBS containing 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
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Short Term Storage: +4°C
Long Term Storage: +4°C
Keep conjugated formats at +4°C. Stable for at least 1 year after receipt when stored at +4°C. - Haltbarkeit
- 12 months
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- Target
- TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))
- Andere Bezeichnung
- TRAIL-R1 (TNFRSF10A Produkte)
- Synonyme
- APO2 antikoerper, CD261 antikoerper, DR4 antikoerper, TRAILR-1 antikoerper, TRAILR1 antikoerper, TNFRSF10A antikoerper, TNF receptor superfamily member 10a antikoerper, tumor necrosis factor receptor superfamily member 26 antikoerper, tumor necrosis factor receptor superfamily, member 10a antikoerper, TNFRSF10A antikoerper, LOC510798 antikoerper
- Hintergrund
- TRAIL-R1 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.
- UniProt
- O00220
- Pathways
- Apoptose, Positive Regulation of Endopeptidase Activity
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