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BMI1 Antikörper
BMI1
Reaktivität: Maus
WB, IHC, IHC (p), ICC
Wirt: Maus
Monoclonal
P9
unconjugated
Produktnummer ABIN1112825
Produktdetails anti-BMI1 Antikörper
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Target
Alle BMI1 Antikörper anzeigen
BMI1
(BMI1 Polycomb Ring Finger Oncogene (BMI1))
Reaktivität
Alle Reaktivitäten für BMI1 Antikörper
Maus
Wirt
Alle Wirte für BMI1 Antikörper
Maus
Klonalität
Alle Klonalitäten für BMI1 Antikörper
Monoklonal
Konjugat
Alle Konjugate für BMI1 Antikörper
Dieser BMI1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für BMI1 Antikörper
Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
Immunogen
Recombinant Polycomb complex protein BMI-1 protein.
Klon
P9
Isotyp
IgG2a
Top Product
Discover our top product BMI1 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
WB (1:1000-5000), IHC-P (1:200), ICC (1:500). Other applications have not been tested. The optimal dilutions should be determined by end user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
TBS (pH7.4), 0.5% BSA, 40% Glycerol and 0.05% Sodium Azide.
Konservierungsmittel
Sodium azide, Thimerosal (Merthiolate)
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 4 °C after thawing (1 week). Aliquot and store at -20 °C for long term (at least one year). Avoid repeated freeze and thaw cycles.
Haltbarkeit
12 months
Details zu BMI1
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Target
BMI1
(BMI1 Polycomb Ring Finger Oncogene (BMI1))
Andere Bezeichnung
Polycomb complex protein BMI-1 (BMI1 Produkte )
Synonyme
FLVI2/BMI1 antikoerper, PCGF4 antikoerper, RNF51 antikoerper, AW546694 antikoerper, Bmi-1 antikoerper, Pcgf4 antikoerper, bmi1 antikoerper, pcgf4 antikoerper, psc1 antikoerper, wu:fb17g03 antikoerper, wu:fd18f06 antikoerper, BMI-1 antikoerper, pcgf4b antikoerper, bmi-1 antikoerper, bmi1-a antikoerper, bmi1-b antikoerper, bmi1b antikoerper, rnf51 antikoerper, xbmi-1 antikoerper, BMI1 proto-oncogene, polycomb ring finger antikoerper, BMI1 polycomb ring finger oncogene antikoerper, Bmi1 polycomb ring finger oncogene antikoerper, bmi1 polycomb ring finger oncogene 1a antikoerper, bmi1 polycomb ring finger oncogene 1b antikoerper, BMI1 proto-oncogene, polycomb ring finger L homeolog antikoerper, BMI1 antikoerper, LOC100230513 antikoerper, Bmi1 antikoerper, bmi1a antikoerper, bmi1b antikoerper, bmi1.L antikoerper
Hintergrund
BMI1 has been reported as an oncogene by regulating p16 and p19, which are cell cycle inhibitor genes. BMI1 knockout in mice results in defects in hematopoiesis, skeletal patterning, neurological functions, and development of the cerebellum. It is a component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. BMI1 is necessary for efficient self-renewing cell divisions of adult hematopoietic stem cells as well as adult peripheral and central nervous system neural stem cells. BMI1 is also thought to inhibit ageing in neurons through the suppression of p53.
Pathways
Zellzyklus , Autophagie
Zuletzt angesehen
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