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SMAD1 Antikörper (C-Term)
SMAD1
Reaktivität: Human, Ratte
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN1109057
Produktdetails anti-SMAD1 Antikörper
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Target
Alle SMAD1 Antikörper anzeigen
SMAD1
(SMAD, Mothers Against DPP Homolog 1 (SMAD1))
Bindungsspezifität
Alle Epitope für SMAD1 Antikörper
AA 442-456, C-Term
Reaktivität
Alle Reaktivitäten für SMAD1 Antikörper
Human, Ratte
Wirt
Alle Wirte für SMAD1 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für SMAD1 Antikörper
Polyklonal
Konjugat
Alle Konjugate für SMAD1 Antikörper
Dieser SMAD1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für SMAD1 Antikörper
Western Blotting (WB)
Spezifität
This antibody detects SMAD1/2/3/5 (C-term, 442-456). No cross reactivity with other proteins.
Kreuzreaktivität (Details)
Species reactivity (tested):Human, rat
Aufreinigung
Immunogen affinity purified
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminal of human Smad 1,2,3,5 (442-456aa), identical to the related rat sequence
Isotyp
IgG
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Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Rekonstitution
0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Buffer
5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
Konservierungsmittel
Sodium azide, Thimerosal (Merthiolate)
Vorsichtsmaßnahmen
This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Details zu SMAD1
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Target
SMAD1
(SMAD, Mothers Against DPP Homolog 1 (SMAD1))
Andere Bezeichnung
SMAD1 (SMAD1 Produkte )
Synonyme
MLP antikoerper, Xmad1 antikoerper, Xsmad1 antikoerper, bsp1 antikoerper, jv4-1 antikoerper, jv41 antikoerper, madh1 antikoerper, madr1 antikoerper, smad-1 antikoerper, MADH1 antikoerper, fb39h09 antikoerper, wu:fb39h09 antikoerper, wu:fb97e04 antikoerper, 2/23 antikoerper, CG12399 antikoerper, Dmel\\CG12399 antikoerper, E(zen)2 antikoerper, En(vvl) antikoerper, MAD antikoerper, Mat antikoerper, P-Mad antikoerper, P-mad antikoerper, PMad antikoerper, Smad antikoerper, Smad1 antikoerper, apg antikoerper, c28 antikoerper, dMAD antikoerper, dMad antikoerper, l(2)K00237 antikoerper, l(2)k00237 antikoerper, mad antikoerper, p-Mad antikoerper, pMAD antikoerper, pMad antikoerper, pSmad antikoerper, BSP-1 antikoerper, BSP1 antikoerper, JV4-1 antikoerper, JV41 antikoerper, MADR1 antikoerper, AI528653 antikoerper, Madh1 antikoerper, Madr1 antikoerper, Mlp1 antikoerper, MusMLP antikoerper, smad1 antikoerper, xmad antikoerper, SMAD family member 1 antikoerper, Mothers against dpp antikoerper, SMAD family member 1 L homeolog antikoerper, smad1 antikoerper, SMAD1 antikoerper, Mad antikoerper, Smad1 antikoerper, smad1.L antikoerper
Hintergrund
SMADs are proteins that modulate the activity of transforming growth factor beta ligands. The SMADs,often in complex with other SMADs/CoSMAD, act as transcription factors that regulate the expression of certain genes. Zhu, H et al concluded that targeted ubiquitination of SMADs may serve to control both embryonic development and a wide variety of cellular responses to TGF-beta signals. R-Smads or receptor regulated Smads are a class of proteins that include SMAD1, SMAD2, SMAD3, SMAD5, and SMAD8. In response to signals by the TGF-β superfamily of ligands these proteins associate with receptor kinases and are phosphorylated at an SSXS motif at their extreme C-terminus. These proteins then typically bind to the common mediator Smad or co-SMAD SMAD4.Synonyms: 2, 3, 5, SMAD1, SMAD2, SMAD3, SMAD5
Gen-ID
4086
NCBI Accession
NP_001003688
UniProt
Q15797
Pathways
Stem Cell Maintenance , Regulation of Muscle Cell Differentiation , Skeletal Muscle Fiber Development
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