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SMAD1 Produkte

(SMAD, Mothers Against DPP Homolog 1 (SMAD1))

Kategorien

The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008].

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Ausgewählte SMAD1 Kategorien

SMAD1 Antikörper

High quality antibodies with extensive validation data.

SMAD1 ELISA Kits

Reliable ELISA kits for a wide range of species.

SMAD1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene SMAD1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation IF, IHC, WB
Validierungen
  • (1)
  • (7)
Kat. Nr. ABIN3021439
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation IF, IHC (p), ELISA, WB
Validierungen
  • (1)
  • (9)
Kat. Nr. ABIN517610
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation IF, IHC, ELISA, WB
Validierungen
  • (6)
Kat. Nr. ABIN3032610
Menge 0.4 mL
Datenblatt Datenblatt

Empfohlene SMAD1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6959518
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6970248
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6970247
Menge 96 tests
Datenblatt Datenblatt

Empfohlene SMAD1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (2)
  • (1)
Kat. Nr. ABIN1320591
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3077050
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3120972
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren SMAD1 Produkten

Kong, Liang, Chen, Yang, Liu, Li, Feng, Wu, Liu, Tang, Yu, Ou, Lu, Yan: "Hyaluronan negatively regulates vascular calcification involving BMP2 signaling." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 98, Issue 10, pp. 1320-1332, (2018) (PubMed).

Yi, Yu, Yang, Miron, Zhang: "Tcf12, A Member of Basic Helix-Loop-Helix Transcription Factors, Mediates Bone Marrow Mesenchymal Stem Cell Osteogenic Differentiation In Vitro and In Vivo." in: Stem cells (Dayton, Ohio), Vol. 35, Issue 2, pp. 386-397, (2017) (PubMed).

Qu, Zheng, Gan, Lian, He, Li, Yuan, Yang, Li, Ji, Yan, Xu, Guo: "MiR-199a-3p suppresses proliferation and invasion of prostate cancer cells by targeting Smad1." in: Oncotarget, Vol. 8, Issue 32, pp. 52465-52473, (2017) (PubMed).

Xu, Ni, Huang, Meng, He, Zhang, Li: "NLRC5 Mediates IL-6 and IL-1? Secretion in LX-2 Cells and Modulated by the NF-?B/Smad3 Pathway." in: Inflammation, Vol. 38, Issue 5, pp. 1794-804, (2015) (PubMed).

Korish, Abdel Gader, Korashy, Al-Drees, Alhaider, Arafah: "Camel milk attenuates the biochemical and morphological features of diabetic nephropathy: inhibition of Smad1 and collagen type IV synthesis." in: Chemico-biological interactions, Vol. 229, pp. 100-8, (2015) (PubMed).

Nakajima, Yanagihara, Nishii: "Temporal and regional patterns of Smad activation in the rat hippocampus following global ischemia." in: Journal of the neurological sciences, Vol. 337, Issue 1-2, pp. 25-37, (2014) (PubMed).

Suh, Lee, Lee, Chung, Park: "Simultaneous imaging and restoration of cell function using cell permeable peptide probe." in: Biomaterials, Vol. 35, Issue 24, pp. 6287-98, (2014) (PubMed).

Shi, Jiang, Ma, Xie, Duan, Chen, Song, Yu, Liu, Zhu, Zheng: "Dexamethasone attenuates bleomycin-induced lung fibrosis in mice through TGF-?, Smad3 and JAK-STAT pathway." in: International journal of clinical and experimental medicine, Vol. 7, Issue 9, pp. 2645-50, (2014) (PubMed).

Tao, Hu, Li, Liu, Wu, Li, Fu, Wei, Luo: "Tranilast prevents the progression of chronic cyclosporine nephrotoxicity through regulation of transforming growth factor ?/Smad pathways." in: Transplantation proceedings, Vol. 43, Issue 5, pp. 1985-8, (2011) (PubMed).

Trinh, Barengo, Naora: "Homeodomain protein DLX4 counteracts key transcriptional control mechanisms of the TGF-? cytostatic program and blocks the antiproliferative effect of TGF-?." in: Oncogene, Vol. 30, Issue 24, pp. 2718-29, (2011) (PubMed).

Synonyme und alternative Namen zu SMAD1

SMAD family member 1 (smad1), SMAD family member 1 (SMAD1), Mothers against dpp (Mad), SMAD family member 1 (Smad1), SMAD family member 1 L homeolog (smad1.L), 2/23, AI528653, apg, BSP-1, bsp1, BSP1, c28, CG12399, dMAD, dMad, Dmel\\CG12399, E(zen)2, En(vvl), fb39h09, jv4-1, JV4-1, jv41, JV41, l(2)K00237, l(2)k00237, MAD, mad, madh1, MADH1, Madh1, madr1, MADR1, Madr1, Mat, MLP, Mlp1, MusMLP, P-Mad, P-mad, p-Mad, PMad, pMAD, pMad, pSmad, Smad, smad-1, Smad1, smad1, wu:fb39h09, wu:fb97e04, xmad, Xmad1, Xsmad1

Bezeichner auf Proteinebene für SMAD1

  • MAD homolog 1
  • SMAD, mothers against DPP homolog 1
  • mothers against decapentaplegic homolog 1
  • mothers against decapentaplegic-like protein 1
  • MAD (mothers against decapentaplegic, Drosophila) homolog 1
  • SMA- and MAD-related protein 1
  • SMAD 1
  • SMAD family member 1
  • mothers against DPP homolog 1
  • CG12399-PA
  • CG12399-PB
  • Mad-PA
  • Mad-PB
  • apang
  • mother against decapentaplegic
  • mothers against decapentaplegi
  • mothers against decapentaplegic
  • mothers against dpp
  • phospho-Smad
  • phosphoSmad
  • phosphorylated smad
  • MAD, mothers against decapentaplegic homolog 1
  • Mad-related protein 1
  • TGF-beta signaling protein 1
  • transforming growth factor-beta signaling protein 1
  • transforming growth factor-beta-signaling protein 1
  • Smad 1
  • dwarfin-A
  • dwf-A
  • mMad1
  • mad-related protein 1
  • mothers-against-DPP-related 1
  • MAD homolog1 (mothers against decapentaplegic, Drosophila)
  • mothers against DPP
  • BMP pathway effector
  • BMP signal transducer Smad1
  • Sma- and Mad-related protein 1
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