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SMAD7 Produkte

(SMAD, Mothers Against DPP Homolog 7 (SMAD7))
The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010].

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Ausgewählte SMAD7 Kategorien

SMAD7 Antikörper

High quality antibodies with extensive validation data.

SMAD7 ELISA Kits

Reliable ELISA kits for a wide range of species.

SMAD7 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene SMAD7 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), FACS
Validierungen
  • (3)
  • (5)
Kat. Nr. ABIN670206
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC (p)
Validierungen
  • (2)
  • (4)
Kat. Nr. ABIN517666
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IF
Validierungen
  • (5)
Kat. Nr. ABIN7270356
Menge 100 μL
Datenblatt Datenblatt

Empfohlene SMAD7 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6959527
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6970256
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6970255
Menge 96 tests
Datenblatt Datenblatt

Empfohlene SMAD7 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1320614
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3095441
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3131491
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren SMAD7 Produkten

Tang, Reissig, Glasmacher, Regen, Wanke, Nikolaev, Gerlach, Popp, Karram, Fantini, Schattenberg, Galle, Neurath, Weigmann, Kurschus, Hövelmeyer, Waisman: "Alternative Splice Forms of CYLD Mediate Ubiquitination of SMAD7 to Prevent TGFB Signaling and Promote Colitis." in: Gastroenterology, Vol. 156, Issue 3, pp. 692-707.e7, (2019) (PubMed).

Yang, Ding, Xu, Chen, Ding: "MicroRNA-15a inhibition protects against hypoxia/reoxygenation-induced apoptosis of cardiomyocytes by targeting mothers against decapentaplegic homolog 7." in: Molecular medicine reports, Vol. 15, Issue 6, pp. 3699-3705, (2017) (PubMed).

Yang, Luo, Zhu, Zhou, Wang, Xue, Zhang, Cai, Chen, Ma, Chen, Wang, Luo, Liu, Zhao: "Chlorogenic Acid Inhibits Liver Fibrosis by Blocking the miR-21-Regulated TGF-β1/Smad7 Signaling Pathway in Vitro and in Vivo." in: Frontiers in pharmacology, Vol. 8, pp. 929, (2017) (PubMed).

Zhuang, Yang, Ma, Han, Wang, Zhao, Wu, Qu: "MicroRNA-92b promotes hepatocellular carcinoma progression by targeting Smad7 and is mediated by long non-coding RNA XIST." in: Cell death & disease, Vol. 7, pp. e2203, (2016) (PubMed).

Aparecida-Silva, Borges, Kessler, Dias, Moreira, Kalil, Gutierrez: "Transforming growth factor-β1 SMAD effectors and medial cell number in ascending aorta diseases." in: Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology, Vol. 25, Issue 3, pp. 240-6, (2016) (PubMed).

Shang, Liu, Liu, Zhang, Mu, Zhu, Liang, Zhai, Ding, Li, Wen: "Acetyl-11-Keto-β-Boswellic Acid Attenuates Prooxidant and Profibrotic Mechanisms Involving Transforming Growth Factor-β1, and Improves Vascular Remodeling in Spontaneously Hypertensive Rats." in: Scientific reports, Vol. 6, pp. 39809, (2016) (PubMed).

Piotrowski, Kiszałkiewicz, Górski, Antczak, Górski, Pastuszak-Lewandoska, Migdalska-Sęk, Domańska-Senderowska, Nawrot, Czarnecka, Kurmanowska, Brzeziańska-Lasota: "Immunoexpression of TGF-β/Smad and VEGF-A proteins in serum and BAL fluid of sarcoidosis patients." in: BMC immunology, Vol. 16, pp. 58, (2015) (PubMed).

Liu, Shi, Yang, Zhao, Du, Zou, Yu: "Synchronous alteration pattern between serine-threonine kinase receptor-associated protein and Smad7 in pilocarpine-induced rats of epilepsy." in: Synapse (New York, N.Y.), Vol. 68, Issue 6, pp. 275-82, (2014) (PubMed).

Gao, Aqie, Zhu, Chen, Xu, Jiang, Xu: "MG132 ameliorates kidney lesions by inhibiting the degradation of Smad7 in streptozotocin-induced diabetic nephropathy." in: Journal of diabetes research, Vol. 2014, pp. 918396, (2014) (PubMed).

Kayalar, Oztay: "Retinoic acid induced repair in the lung of adult hyperoxic mice, reducing transforming growth factor-β1 (TGF-β1) mediated abnormal alterations." in: Acta histochemica, Vol. 116, Issue 5, pp. 810-9, (2014) (PubMed).

Synonyme und alternative Namen zu SMAD7

SMAD family member 7 (SMAD7), SMAD family member 7 (Smad7), SMAD family member 7 L homeolog (smad7.L), SMAD family member 7 (smad7), CRCS3, MADH7, Madh7, madh7, MADH8, Smad7a, Smad10, wu:fj60c10, xsmad7

Bezeichner auf Proteinebene für SMAD7

  • MAD (mothers against decapentaplegic, Drosophila) homolog 7
  • MAD homolog 8
  • Mothers against decapentaplegic, drosophila, homolog of, 7
  • SMAD, mothers against DPP homolog 7
  • hSMAD7
  • mothers against DPP homolog 8
  • mothers against decapentaplegic homolog 7
  • SMAD family member 7
  • MAD homolog 7
  • SMAD 7
  • madh8
  • mothers against DPP homolog 7
  • mothers against decapentaplegic homolog 8
  • mothers against DPP 7
  • mothers against decapentaplegic-like protein 7
  • MAD, mothers against decapentaplegic homolog 7
  • fj60c10
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