PTGDS Antikörper (Internal Region)

Produktnummer ABIN1108786

Produktdetails anti-PTGDS Antikörper

Target: PTGDS (Prostaglandin D2 Synthase (PTGDS))

Bindungsspezifität: Internal Region

Reaktivität: Maus

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser PTGDS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequenz: C-YSRTQTLKDE LKEK

Spezifität: This antibody recognizes Mouse PTGDS. Other species not tested.

Kreuzreaktivität (Details): Species reactivity (tested):Mouse.

Aufreinigung: Affinity Chromatography

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_032989.2. Genename: Ptgds

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PTGDS

Target: PTGDS (Prostaglandin D2 Synthase (PTGDS))

Andere Bezeichnung: PTGDS (PTGDS Produkte)

Synonyme: 6PGD antikoerper, GSTS antikoerper, GSTS1-1 antikoerper, PGD2 antikoerper, PGDS antikoerper, L-PGDS antikoerper, LPGDS antikoerper, PDS antikoerper, PGDS2 antikoerper, H-PGDS antikoerper, Ptgds2 antikoerper, 21kDa antikoerper, Ptgs3 antikoerper, PH2DISO antikoerper, phosphogluconate dehydrogenase antikoerper, hematopoietic prostaglandin D synthase antikoerper, prostaglandin D2 synthase antikoerper, prostaglandin D2 synthase (brain) antikoerper, prostaglandin D synthase antikoerper, prostaglandin D2 synthase 21kDa (brain) antikoerper, PGD antikoerper, HPGDS antikoerper, PTGDS antikoerper, Hpgds antikoerper, Ptgds antikoerper, LOC100009453 antikoerper

Hintergrund: The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. PTGDS has also been implicated in the development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement (NREM) sleep. It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system. PTGDS is the most abundant protein in the cerebral spinal fluid and recent evidence suggests that PTGDS acts as a Beta-Amyloid chaperone and may have a role in the deposition of Ab plaques in Alzheimer's disease.Synonyms: Beta-trace protein, Cerebrin-28, Glutathione-independent PGD synthase, Lipocalin-type prostaglandin-D synthase, PDS, PGD2 synthase, PGDS, PGDS2, Prostaglandin D synthase, Prostaglandin-D2 synthase, Prostaglandin-H2 D-isomerase

Molekulargewicht: 21.1 kDa (NP_032989.2).

Gen-ID: 19215

NCBI Accession: NP_032989