IL12A Antikörper

Produktnummer ABIN1107846

Produktdetails anti-IL12A Antikörper

Target: IL12A (Interleukin 12 alpha (IL12A))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL12A Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA)

Spezifität: Recognises both natural and recombinant protein (no cross reaction with IL-12 and IL-27).

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Ion Exchange Chromatography

Immunogen: EBI3 recombinant protein and IL-35/Fc recombinant protein. Myeloma X63/AG.8653 x Balb/c node cells.

Klon: B-S35

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS without carriers and preservatives

Konservierungsmittel: Without preservative

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu IL12A

Target: IL12A (Interleukin 12 alpha (IL12A))

Andere Bezeichnung: Interleukin-12 alpha / IL12A (IL12A Produkte)

Synonyme: CLMF antikoerper, IL-12A antikoerper, NFSK antikoerper, NKSF1 antikoerper, P35 antikoerper, CLMF2 antikoerper, IL-12B antikoerper, NKSF antikoerper, NKSF2 antikoerper, p40 antikoerper, Il-12b antikoerper, Il12p40 antikoerper, Il-12p40 antikoerper, Il12 antikoerper, IL-12p40 antikoerper, IL-12p35 antikoerper, Il-12a antikoerper, Ll12a antikoerper, p35 antikoerper, IL12p35 antikoerper, Il-12 p35 antikoerper, IL12p40 antikoerper, IL12 antikoerper, IL-12 p35 antikoerper, interleukin 12A antikoerper, interleukin 12B antikoerper, interleukin 12b antikoerper, interleukin 12a antikoerper, Interleukin 12 level antikoerper, IL12A antikoerper, IL12B antikoerper, Il12b antikoerper, Il12a antikoerper, IL12 antikoerper, il12a antikoerper

Hintergrund: IL-35 or Interleukin 35 is a cytokine belonging to the IL12 family, that is produced by regulatory T cells. It is a dimeric protein composed of IL-12-alpha and IL-27-beta chains. Members of this class of cytokines are important in influencing T helper cell differentiation and supressing inflammatory response. IL-35 is known to play an essential role in immune regulation of the CD4+CD25+ regulatory T (Treg) cells, from which IL-35 is also specifically produced. IL-35 is able to expand CD4+CD25+ Treg cells whereas it can inhibit proliferation of CD4+CD25- effector T (Teff) cells and development of proinflammatory Th17 cells, suppressing inflammatory responses.Synonyms: CLMF p35, Cytotoxic lymphocyte maturation factor 35 kDa subunit, IL-12 subunit p35, IL-12A, NK cell stimulatory factor chain 1, NKSF1

Gen-ID: 3592

NCBI Accession: NP_000873

UniProt: P29459

Pathways: JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation