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GFAP Antikörper (C-Term)
GFAP
Reaktivität: Human, Ratte, Maus
WB, IHC (p)
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN1107343
Produktdetails anti-GFAP Antikörper
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Target
Alle GFAP Antikörper anzeigen
GFAP
(Glial Fibrillary Acidic Protein (GFAP))
Bindungsspezifität
Alle Epitope für GFAP Antikörper
C-Term
Reaktivität
Alle Reaktivitäten für GFAP Antikörper
Human, Ratte, Maus
Wirt
Alle Wirte für GFAP Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für GFAP Antikörper
Polyklonal
Konjugat
Alle Konjugate für GFAP Antikörper
Dieser GFAP Antikörper ist unkonjugiert
Applikation
Alle Applikationen für GFAP Antikörper
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Spezifität
This antibody detects GFAP at C-term. No cross reactivity with other proteins.
Kreuzreaktivität (Details)
Species reactivity (tested):Human, Mouse, Rat.
Aufreinigung
Immunogen affinity purified
Immunogen
Synthetic peptide corresponding to a sequence at the C-terminal of human GFAP .Remarks: Sequence is identical to the related rat and mouse sequence.
Isotyp
IgG
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Rekonstitution
0.2 mL of distilled water will yield a concentration of 0.5 mg/mL.
Buffer
0.2 mg Na2HPO4, 0.9 mg NaCl, 0.05 mg Thimerosal, 0.05 mg Sodium Azide, 5 mg BSA
Konservierungsmittel
Sodium azide, Thimerosal (Merthiolate)
Vorsichtsmaßnahmen
This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Details zu GFAP
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Target
GFAP
(Glial Fibrillary Acidic Protein (GFAP))
Andere Bezeichnung
GFAP (GFAP Produkte )
Synonyme
GFAP antikoerper, AI836096 antikoerper, cb345 antikoerper, etID36982.3 antikoerper, gfapl antikoerper, wu:fb34h11 antikoerper, wu:fk42c12 antikoerper, xx:af506734 antikoerper, zgc:110485 antikoerper, glial fibrillary acidic protein antikoerper, GFAP antikoerper, LOC100136168 antikoerper, gfap antikoerper, Gfap antikoerper
Hintergrund
GGlial fibrillary acidic protein (GFAP) is an intermediate-filament (IF) protein that is highly specific for cells of astroglial lineage, although its tissue-specific role is speculative. GFAP has been located in rat kidney glomeruli and peritubular fibroblasts, leydig cells of testis, skin keratinocytes, osteocytes of bones, chondrocytes of epiglottis, bronchus, and stellate-shaped cells of the pancreas and liver. Its expression is essential for normal white matter architecture and blood-brain barrier integrity, and its absence leads to late-onset CNS dysmyelination. GFAP has also been shown to play a role in mitosis by adjusting the filament network present in the cell. During mitosis, there is an increase in the amount of phosphorylated GFAP, and a movement of this modified protein to the cleavage furrow.Synonyms: Glial Fibrillary Acidic Protein
Gen-ID
2670
NCBI Accession
NP_001124491
UniProt
P14136
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