GFAP Antikörper (C-Term)
Kurzübersicht für GFAP Antikörper (C-Term) (ABIN3020751)
Target
Alle GFAP Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Sequenz
- RGTNESLERQ MREQEERHVR EAASYQEALA RLEEEGQSLK DEMARHLQEY QDLLNVKLAL DIEIATYRKL LEGEENRITI PVQTFSNLQI RETSLDTKSV SEGHLKRNIV VKTVEMRDGE VIKESKQEHK DVM
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human GFAP (NP_002046.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid freeze / thaw cycles
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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: "TPD52L2 impacts proliferation, invasiveness and apoptosis of glioblastoma cells via modulation of wnt/β-catenin/snail signaling." in: Carcinogenesis, Vol. 39, Issue 2, pp. 214-224, (2018) (PubMed).
: "Interleukin-17A Acts to Maintain Neuropathic Pain Through Activation of CaMKII/CREB Signaling in Spinal Neurons." in: Molecular neurobiology, Vol. 53, Issue 6, pp. 3914-3926, (2016) (PubMed).
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- GFAP (Glial Fibrillary Acidic Protein (GFAP))
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Andere Bezeichnung
- GFAP
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Hintergrund
- This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.,ALXDRD,GFAP,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Intermediate Filaments,Neuroscience,Cell Type Marker,Stem Cells,Neural Stem Cells,Astrocyte marker,Microglia marker,GFAP
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Molekulargewicht
- 49 kDa/50 kDa
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Gen-ID
- 2670
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UniProt
- P14136
Target
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