GFAP Antikörper (C-Term)

Produktnummer ABIN3020751

Produktdetails anti-GFAP Antikörper

Target: GFAP (Glial Fibrillary Acidic Protein (GFAP))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GFAP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: RGTNESLERQ MREQEERHVR EAASYQEALA RLEEEGQSLK DEMARHLQEY QDLLNVKLAL DIEIATYRKL LEGEENRITI PVQTFSNLQI RETSLDTKSV SEGHLKRNIV VKTVEMRDGE VIKESKQEHK DVM

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human GFAP (NP_002046.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-GFAP Antikörper (ABIN3020751)

Qiang, Jun-Jie, Hai, Hong, Bing-Xi, Lei, Wei, Ya-Wei, Huang, Song-Tao, Yun-Tao: "TPD52L2 impacts proliferation, invasiveness and apoptosis of glioblastoma cells via modulation of wnt/β-catenin/snail signaling." in: Carcinogenesis, Vol. 39, Issue 2, pp. 214-224, (2018) (PubMed).

Yao, Weng, Zhang, Feng, Lin, Yao: "Interleukin-17A Acts to Maintain Neuropathic Pain Through Activation of CaMKII/CREB Signaling in Spinal Neurons." in: Molecular neurobiology, Vol. 53, Issue 6, pp. 3914-3926, (2016) (PubMed).

Details zu GFAP

Target: GFAP (Glial Fibrillary Acidic Protein (GFAP))

Andere Bezeichnung: GFAP (GFAP Produkte)

Synonyme: GFAP antikoerper, AI836096 antikoerper, cb345 antikoerper, etID36982.3 antikoerper, gfapl antikoerper, wu:fb34h11 antikoerper, wu:fk42c12 antikoerper, xx:af506734 antikoerper, zgc:110485 antikoerper, glial fibrillary acidic protein antikoerper, GFAP antikoerper, LOC100136168 antikoerper, gfap antikoerper, Gfap antikoerper

Hintergrund: This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.,ALXDRD,GFAP,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Intermediate Filaments,Neuroscience,Cell Type Marker,Stem Cells,Neural Stem Cells,Astrocyte marker,Microglia marker,GFAP

Molekulargewicht: 49 kDa/50 kDa

Gen-ID: 2670

UniProt: P14136