Cytokeratin 18 Antikörper

Produktnummer ABIN1106917

Produktdetails anti-Cytokeratin 18 Antikörper

Target: Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Reaktivität: Human, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Cytokeratin 18 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität: Recognizes Cytokeratin Peptide 18. No cross reactivity with other proteins.

Aufreinigung: Affinity Chromatography

Immunogen: Human epidermal carcinoma A-431 and MCF-7 Human breast cancer cell lines.

Klon: CK-18

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with 1.2 % Sodium Acetate or neutral PBS.

Konzentration: 0.1 mg/mL

Buffer: 1.2 % Sodium Acetate containing 2 mg BSA and 0.01 mg Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody after reconstitution at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Cytokeratin 18

Target: Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Andere Bezeichnung: Cytokeratin 18 (KRT18 Produkte)

Synonyme: CK18 antikoerper, K18 antikoerper, Krt1-18 antikoerper, CYK18 antikoerper, DreK18 antikoerper, cb83 antikoerper, dapk1 antikoerper, sb:cb83 antikoerper, wu:fa13f02 antikoerper, wu:fb36b04 antikoerper, krt18 antikoerper, MGC64569 antikoerper, MGC75922 antikoerper, KRT18 antikoerper, CK-18-A antikoerper, K18-A antikoerper, NC-11 antikoerper, cyk18 antikoerper, k18 antikoerper, krt18-a antikoerper, krt18-b antikoerper, krt18a antikoerper, xkendob antikoerper, keratin 18 antikoerper, keratin 18, type I L homeolog antikoerper, keratin 18, type I antikoerper, keratin, type I cytoskeletal 18 antikoerper, K18, simple type I keratin antikoerper, Keratin, type I cytoskeletal 18 antikoerper, keratin 18, type I S homeolog antikoerper, Krt18 antikoerper, KRT18 antikoerper, krt18 antikoerper, krt18.L antikoerper, LOC700569 antikoerper, LOC100136778 antikoerper, k1c18 antikoerper, LOC100008885 antikoerper, krt18.S antikoerper

Hintergrund: Intermediate filaments (IFs) are a structurally related family of cellular proteins that appear to be intimately involved with the cytoskeleton. Human keratin 18(KRT18) and the homologous mouse Endo B are type I IF protein subunits whose expression is restricted in adults to a variety of simple epithelial tissues. The KRT18 gene is 3,791 bp long and the keratin 18 protein is coded for by 7 exons. The K18 gene is 3791 bp in length and the K18 protein is coded for by seven exons. By Southern blotting using the genomic DNA PCR product, the gene for keratin 18 is assigned to chromosome 12. Mutation of human keratin 18 in association with cryptogenic cirrhosisSynonyms: CK18, CYK18, Cell proliferation-inducing gene 46 protein, Cytokeratin-18, K18, KRT18, Keratin 18, Keratin type I cytoskeletal 18, Keratin-18

Gen-ID: 3875

NCBI Accession: NP_000215

UniProt: P05783

Pathways: Apoptose, Caspase Kaskade in der Apoptose