Cytokeratin 18 Antikörper (AA 53-150)

Produktnummer ABIN676973

Produktdetails anti-Cytokeratin 18 Antikörper

Target: Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Bindungsspezifität: AA 53-150

Reaktivität: Human, Maus, Ratte, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cytokeratin 18 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Schwein, Ratte

Homologie: Dog,Cow,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CK18

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-Cytokeratin 18 Antikörper (ABIN676973)

Fagundes, Fernandes, Paraense, de Farias-Junior, Teixeira, Alves-Junior, Pinheiro, Crespo-López, Maia, Lima: "Binge Drinking of Ethanol during Adolescence Induces Oxidative Damage and Morphological Changes in Salivary Glands of Female Rats." in: Oxidative medicine and cellular longevity, Vol. 2016, pp. 7323627, (2017) (PubMed).

Liu, Feng, Dong, Yang, Li, Chen, Zhang, Wang, Zhou, Zhao: "Administration of BMSCs with muscone in rats with gentamicin-induced AKI improves their therapeutic efficacy." in: PLoS ONE, Vol. 9, Issue 5, pp. e97123, (2014) (PubMed).

Zeng, Zhang, Li, Yang, Chen, Liu: "A new method to isolate and culture rat kupffer cells." in: PLoS ONE, Vol. 8, Issue 8, pp. e70832, (2013) (PubMed).

Details zu Cytokeratin 18

Target: Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Andere Bezeichnung: CK18 (KRT18 Produkte)

Synonyme: CK18 antikoerper, K18 antikoerper, Krt1-18 antikoerper, CYK18 antikoerper, DreK18 antikoerper, cb83 antikoerper, dapk1 antikoerper, sb:cb83 antikoerper, wu:fa13f02 antikoerper, wu:fb36b04 antikoerper, krt18 antikoerper, MGC64569 antikoerper, MGC75922 antikoerper, KRT18 antikoerper, CK-18-A antikoerper, K18-A antikoerper, NC-11 antikoerper, cyk18 antikoerper, k18 antikoerper, krt18-a antikoerper, krt18-b antikoerper, krt18a antikoerper, xkendob antikoerper, keratin 18 antikoerper, keratin 18, type I L homeolog antikoerper, keratin 18, type I antikoerper, keratin, type I cytoskeletal 18 antikoerper, K18, simple type I keratin antikoerper, Keratin, type I cytoskeletal 18 antikoerper, keratin 18, type I S homeolog antikoerper, Krt18 antikoerper, KRT18 antikoerper, krt18 antikoerper, krt18.L antikoerper, LOC700569 antikoerper, LOC100136778 antikoerper, k1c18 antikoerper, LOC100008885 antikoerper, krt18.S antikoerper

Hintergrund:

Synonyms: K18, CYK18, Keratin, type I cytoskeletal 18, Cell proliferation-inducing gene 46 protein, Cytokeratin-18, CK-18, Keratin-18, KRT18, PIG46

Background: Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.

Gen-ID: 3875

UniProt: P05783

Pathways: Apoptose, Caspase Kaskade in der Apoptose