FGFR2 Antikörper (C-Term)

Produktnummer ABIN1106281

Produktdetails anti-FGFR2 Antikörper

Target: FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FGFR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: Recognizes CD332 / FGFR-2. No cross reactivity with other proteins.

Kreuzreaktivität (Details): Species reactivity (expected):Rat.
Species reactivity (tested):Human, Mouse.

Aufreinigung: Immunoaffinity Chromatography

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminal of Human FGFR2, identical to the related Rat and Mouse sequence.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with 0.2 mL of distilled water to yield a concentration of 0.5 mg/mL.

Konzentration: 0.5 mg/mL

Buffer: 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg Sodium Azide

Konservierungsmittel: Sodium azide, Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody after reconstitution at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu FGFR2

Target: FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))

Andere Bezeichnung: CD332 / FGFR-2 (FGFR2 Produkte)

Synonyme: FGFR2 antikoerper, FGFR2IIIb antikoerper, bek antikoerper, bfr-1 antikoerper, cd332 antikoerper, cek3 antikoerper, cfd1 antikoerper, ect1 antikoerper, fgfr-2 antikoerper, jws antikoerper, k-sam antikoerper, kgfr antikoerper, tk14 antikoerper, tk25 antikoerper, xfgfr2 antikoerper, DKFZp469H1521 antikoerper, BBDS antikoerper, BEK antikoerper, BFR-1 antikoerper, CD332 antikoerper, CEK3 antikoerper, CFD1 antikoerper, ECT1 antikoerper, JWS antikoerper, K-SAM antikoerper, KGFR antikoerper, TK14 antikoerper, TK25 antikoerper, AU043015 antikoerper, AW556123 antikoerper, Bek antikoerper, Fgfr-2 antikoerper, Fgfr-7 antikoerper, Fgfr7 antikoerper, KGFRTr antikoerper, svs antikoerper, FGF-R antikoerper, fgfr72IIIb antikoerper, FGFR antikoerper, fc56c05 antikoerper, wu:fc56c05 antikoerper, fibroblast growth factor receptor 2 antikoerper, fibroblast growth factor receptor 2 L homeolog antikoerper, FGFR2 antikoerper, LOC100084641 antikoerper, fgfr2 antikoerper, Fgfr2 antikoerper, fgfr2.L antikoerper

Hintergrund: Fibroblast growth factor receptor 2 (FGFR2) is a receptor for fibroblast growth factor encoded on a gene residing on chromosome 10. FGFR2 has also been designated as CD332. FGFR2 is a membrane-spanning tyrosine kinase that serves as a high affinity receptor for several members of the fibroblast growth factor (FGF) family. Its signals are absolutely required for vertebrate limb induction and that an FGFR2 signal is essential for the reciprocal regulation loop between FGF8 and FGF10 during limb induction. (1) FGFR2 contributes to the outgrowth, differentiation, and maintenance of the inner cell mass and raise the possibility that this activity is mediated by FGF4 signals transmitted by FGFR2. The role of early FGF signaling in pregastrulation development as a possible adaptation to mammalian (amniote) embryogenesis is discussed. (2)Synonyms: BEK, FGFR2, Fibroblast growth factor receptor 2, KGFR, KSAM, Keratinocyte growth factor receptor 2

Gen-ID: 2263

NCBI Accession: NP_000132

UniProt: P21802

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Growth Factor Binding