×
Aktivieren Sie Javascript in Ihrem Browser, um unsere Webseite optimal zu nutzen.
Integrin beta 2 Antikörper (N-Term)
ITGB2
Reaktivität: Human, Maus, Ratte
WB, IHC (p)
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN1105952
Produktdetails anti-Integrin beta 2 Antikörper
(ausblenden)
Target
Alle Integrin beta 2 (ITGB2) Antikörper anzeigen
Integrin beta 2 (ITGB2)
Bindungsspezifität
Alle Epitope für Integrin beta 2 Antikörper
N-Term
Reaktivität
Alle Reaktivitäten für Integrin beta 2 Antikörper
Human, Maus, Ratte
Wirt
Alle Wirte für Integrin beta 2 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für Integrin beta 2 Antikörper
Polyklonal
Konjugat
Alle Konjugate für Integrin beta 2 Antikörper
Dieser Integrin beta 2 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für Integrin beta 2 Antikörper
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Spezifität
This antibody detects CD18 / ITGB2 (N-term). No cross reactivity with other proteins.
Kreuzreaktivität (Details)
Species reactivity (tested):Human, rat, mouse
Aufreinigung
Immunogen affinity purified
Immunogen
A synthetic peptide mapping at the N-terminal of human Integrin beta2 .Remarks: Sequence differs from the related mouse sequence by five amino acids.
Isotyp
IgG
Top Product
Discover our top product ITGB2 Primärantikörper
Alternativen
(anzeigen)
Anwendungsinformationen
(ausblenden)
Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
(ausblenden)
Rekonstitution
0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Buffer
5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
Konservierungsmittel
Sodium azide, Thimerosal (Merthiolate)
Vorsichtsmaßnahmen
This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Details zu Integrin beta 2
(ausblenden)
Target
Integrin beta 2 (ITGB2)
Andere Bezeichnung
CD18 / ITGB2 (ITGB2 Produkte )
Synonyme
CD18 antikoerper, LAD antikoerper, LCAMB antikoerper, LFA-1 antikoerper, MAC-1 antikoerper, MF17 antikoerper, MFI7 antikoerper, 2E6 antikoerper, AI528527 antikoerper, Cd18 antikoerper, Lfa1 antikoerper, ITGB2 antikoerper, itgb2 antikoerper, itgb2-a antikoerper, itgb2-b antikoerper, integrin subunit beta 2 antikoerper, integrin beta 2 antikoerper, integrin subunit beta 2 S homeolog antikoerper, ITGB2 antikoerper, Itgb2 antikoerper, itgb2.S antikoerper
Hintergrund
The beta-2 integrin chain gene is designated ITGB2 and the leukocyte antigen has been designated CD18. The 3 alpha integrin chains associated individually with the beta-2 chain as a heterodimer have gene designations of ITGAL, ITGAM, and ITGAX, and leukocyte antigen designations of CD11A, CD11B, and CD11C, respectively. The expression of CD18 was increased in lymphoblastoid cells from persons with Down syndrome, consistent with the location of the gene on chromosome 211. The ITGB2 gene spans approximately 40 kb and contains 16 exons and all exon/intron boundaries conform to the GT/AG splicing consensus. Furthermore,ITGB2 was constitutively clustered. Although it was expressed on the cell surface at normal levels and was capable of function following extracellular stimulation, it could not be activated via the Synonyms: 95 subunit beta, Cell surface adhesion glycoproteins LFA-1/CR3/p150, Complement receptor C3 subunit beta, Integrin beta-2, MFI7
Gen-ID
3689
NCBI Accession
NP_000202
UniProt
P05107
Pathways
NF-kappaB Signalweg , Activation of Innate immune Response , Toll-Like Receptors Cascades , Activated T Cell Proliferation
Zuletzt angesehen
(ausblenden)