Hepcidin Antikörper (AA 22-36)

Produktnummer ABIN1101963

Produktdetails anti-Hepcidin Antikörper

Target: Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))

Bindungsspezifität: AA 22-36

Reaktivität: Human, Affe

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser Hepcidin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Marke: IHC-plus™

Spezifität: Human HAMP / Hepcidin.

Homologie: Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey (100%) Marmoset, Panda (80%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide TSGSVFPQQTGQLAE-C from the N-terminus (near) of human HAMP / Hepcidin (NP_066998.1). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey (100%), Marmoset, Panda (80%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (3.75 μg/mL), Peptide-ELISA (1:16000)

Usage: Peptide ELISA: antibody detection limit dilution 1:16000. Western blot: Preliminary experiments gave an approx 28  kDa band in Human Liver lysates after 0.1 μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 9.41  kDa according to NP_066998.1. The 28  kDa band was successfully blocked by incubation with the immunizing peptide.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze-thaw cycles.

Details zu Hepcidin

Target: Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))

Andere Bezeichnung: HAMP / Hepcidin (HAMP Produkte)

Synonyme: HEPC antikoerper, HFE2B antikoerper, LEAP1 antikoerper, PLTR antikoerper, Hepcidin antikoerper, Hamp1 antikoerper, Hepc antikoerper, Hepc1 antikoerper, HAMP antikoerper, hepcidin antikoerper, hamp1 antikoerper, hep1 antikoerper, hepcidin antimicrobial peptide antikoerper, hepcidin-like antikoerper, hepcidin-1 antikoerper, Ham percentage antikoerper, HAMP antikoerper, Hamp antikoerper, hamp antikoerper, LOC100135935 antikoerper, LOC106584587 antikoerper

Hintergrund: Name/Gene ID: HAMP

Synonyms: HAMP, Hepcidin antimicrobial peptide, LEAP-1, LEAP1, HEPC, Hepcidin, HFE2B, PLTR, Putative liver tumor regressor

Gen-ID: 57817

NCBI Accession: NP_066998

UniProt: P81172

Pathways: Hormone Activity, Transition Metal Ion Homeostasis