Hepcidin Antikörper (Internal Region)

Produktnummer ABIN6262147

Produktdetails anti-Hepcidin Antikörper

Target: Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Hepcidin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Spezifität: HAMP Antibody detects endogenous levels of total HAMP.

Homologie: Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human HAMP, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu Hepcidin

Target: Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))

Andere Bezeichnung: HAMP (HAMP Produkte)

Synonyme: HEPC antikoerper, HFE2B antikoerper, LEAP1 antikoerper, PLTR antikoerper, Hepcidin antikoerper, Hamp1 antikoerper, Hepc antikoerper, Hepc1 antikoerper, HAMP antikoerper, hepcidin antikoerper, hamp1 antikoerper, hep1 antikoerper, hepcidin antimicrobial peptide antikoerper, hepcidin-like antikoerper, hepcidin-1 antikoerper, Ham percentage antikoerper, HAMP antikoerper, Hamp antikoerper, hamp antikoerper, LOC100135935 antikoerper, LOC106584587 antikoerper

Hintergrund:

Description: Liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues. Acts by promoting endocytosis and degradation of ferroportin, leading to the retention of iron in iron-exporting cells and decreased flow of iron into plasma. Controls the major flows of iron into plasma: absorption of dietary iron in the intestine, recycling of iron by macrophages, which phagocytose old erythrocytes and other cells, and mobilization of stored iron from hepatocytes (PubMed:22306005).

Gene: HAMP

Molekulargewicht: 9kDa

Gen-ID: 57817

UniProt: P81172

Pathways: Hormone Activity, Transition Metal Ion Homeostasis