FOXA1 Antikörper
-
- Target Alle FOXA1 Antikörper anzeigen
- FOXA1 (Forkhead Box A1 (FOXA1))
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser FOXA1 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), ELISA
- Spezifität
- Multiple isoforms of FOXA1 exists as a result of alternative splicing event.
- Aufreinigung
- Affinity chromatography purified via peptide column
- Immunogen
- Rabbit polyclonal FOXA1 antibody was raised against a 17 amino acid peptide near the center of human FOXA1.
- Isotyp
- IgG
- Top Product
- Discover our top product FOXA1 Primärantikörper
-
-
- Applikationshinweise
- FOXA1 antibody can be used for detection of FOXA1 by Western blot at 1 - 2 μg/mL.
- Kommentare
-
(IN) Forkhead box protein A1
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS containing 0.02 % Sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Lagerung
- 4 °C/-20 °C
-
- Target
- FOXA1 (Forkhead Box A1 (FOXA1))
- Andere Bezeichnung
- FOXA1 (FOXA1 Produkte)
- Synonyme
- HNF3A antikoerper, TCF3A antikoerper, Hnf-3a antikoerper, Hnf3a antikoerper, Tcf-3a antikoerper, Tcf3a antikoerper, fkd7 antikoerper, forkhead-7 antikoerper, HNF3-alpha antikoerper, HNF3alpha antikoerper, fkh2 antikoerper, foxa1 antikoerper, hnf3a antikoerper, tFoxA1 antikoerper, tcf3a antikoerper, xfkh2 antikoerper, fkh antikoerper, FOXA1 antikoerper, Ci-fkh antikoerper, HNF-3a antikoerper, forkhead box A1 antikoerper, forkhead box A1 S homeolog antikoerper, forkhead homolog antikoerper, forkhead box A1 L homeolog antikoerper, FOXA1 antikoerper, Foxa1 antikoerper, foxa1 antikoerper, foxa1.S antikoerper, fkh antikoerper, foxa1.L antikoerper
- Hintergrund
-
FOXA1 is one of three members of the FOXA family, a subset of the forkhead family of transcription factors which play vital roles in development. It has also been implicated in the development of a number of other organs including the androgen and estrogen regulated tissues of the breast and prostate. FOXA1 modulates the transcriptional activity of nuclear hormone receptors and regulates apoptosis by inhibiting the expression of BCL-2. It is an essential protein for the transcriptional activity of both androgen receptor (AR) and estrogen receptor-alpha (ER). FOXA1 plays a pivotal role from early stage cancer through to drug resistant and metastatic disease. FOXA1 is not only an attractive therapeutic target but could potentially function as a novel biomarker.
Synonyms: Forkhead box protein A1, hepatocyte nuclear factor 3-alpha, HNF3A, HNF-3A, HNF-3-alpha, Transcription factor 3A, TCF3A, TCF-3A - Molekulargewicht
- 52 kDa
- Gen-ID
- 3169
- NCBI Accession
- NP_004487
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis
-