FOXA1 Antikörper (AA 367-472)

Produktnummer ABIN561299

Es sind 4+ Publikationen für dieses Produkt verfügbar. Der Maus Monoklonal anti-FOXA1 Antikörper wird verwendet zum Nachweis von FOXA1 in Proben von Human. Er wurde validiert für WB, ELISA, IHC (p) und RNAi.

Kurzübersicht für FOXA1 Antikörper (AA 367-472) (ABIN561299)

Target: FOXA1 (Forkhead Box A1 (FOXA1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FOXA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), RNA Interference (RNAi)

Klon: 2D7

Produktdetails anti-FOXA1 Antikörper

Bindungsspezifität: AA 367-472

Verwendungszweck: Mouse monoclonal antibody raised against a partial recombinant FOXA1.

Sequenz: LASVPASHPA HGLAPHESQL HLKGDPHYSF NHPFSINNLM SSSEQQHKLD FKAYEQALQY SPYGSTLPAS LPLGSASVTT RSPIEPSALE PAYYQGVYSR PVLNTS

Kreuzreaktivität: Human

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: FOXA1 (NP_004487, 367 a.a. ~ 472 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-FOXA1 Antikörper (ABIN561299)

Kobayashi, Iwaya, Moriya, Yamasaki, Tsuda, Yamamoto, Matsubara: "A simple immunohistochemical panel comprising 2 conventional markers, Ki67 and p53, is a powerful tool for predicting patient outcome in luminal-type breast cancer." in: BMC clinical pathology, Vol. 13, pp. 5, (2013) (PubMed).

Braun, Mietzsch, Seibold, Schneeweiss, Schirmacher, Chang-Claude, Peter Sinn, Aulmann: "Intrinsic breast cancer subtypes defined by estrogen receptor signalling-prognostic relevance of progesterone receptor loss." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 26, Issue 9, pp. 1161-71, (2013) (PubMed).

Jacquemier, Charafe-Jauffret, Monville, Esterni, Extra, Houvenaeghel, Xerri, Bertucci, Birnbaum: "Association of GATA3, P53, Ki67 status and vascular peritumoral invasion are strongly prognostic in luminal breast cancer." in: Breast cancer research : BCR, Vol. 11, Issue 2, pp. R23, (2009) (PubMed).

Bretschneider, Brand, Miller, Lowery, Kerin, Gannon, Denger: "Estrogen induces repression of the breast cancer and salivary gland expression gene in an estrogen receptor alpha-dependent manner." in: Cancer research, Vol. 68, Issue 1, pp. 106-14, (2008) (PubMed).

Details zu FOXA1

Target: FOXA1 (Forkhead Box A1 (FOXA1))

Andere Bezeichnung: FOXA1

Hintergrund: Full Gene Name: forkhead box A1
Synonyms: HNF3A,MGC33105,TCF3A

Gen-ID: 3169

NCBI Accession: NM_004496

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis