IL1RN Antikörper (AA 26-177) (Biotin)

Produktnummer ABIN1045783

Produktdetails anti-IL1RN Antikörper (Biotin)

Target: IL1RN (Interleukin 1 Receptor Antagonist (IL1RN))

Bindungsspezifität: AA 26-177

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL1RN Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Interleukin-1 receptor antagonist protein (26-177AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid freeze and thaw cycles.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu IL1RN

Target: IL1RN (Interleukin 1 Receptor Antagonist (IL1RN))

Andere Bezeichnung: IL1RN (IL1RN Produkte)

Synonyme: DIRA antikoerper, ICIL-1RA antikoerper, IL-1RN antikoerper, IL-1ra antikoerper, IL-1ra3 antikoerper, IL1F3 antikoerper, IL1RA antikoerper, IRAP antikoerper, MVCD4 antikoerper, IRAP1 antikoerper, IL1RN antikoerper, IL-1RA antikoerper, F630041P17Rik antikoerper, interleukin 1 receptor antagonist antikoerper, interleukin 1 receptor antagonist-like antikoerper, IL1RN antikoerper, Il1rn antikoerper, IL1RNL antikoerper

Hintergrund:

Background: Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2, however, the physiological relevance of the latter association is unsure.

Aliases: DIRA antibody, F630041P17Rik antibody, ICIL 1RA antibody, ICIL-1RA antibody, ICIL1RA antibody, IL-1ra antibody, IL-1ra3 antibody, IL-1RN antibody, IL1 inhibitor antibody, IL1F3 antibody, IL1RA antibody, IL1RA_HUMAN antibody, IL1RN (IL1F3) antibody, IL1RN antibody, Interleukin 1 receptor antagonist antibody, Interleukin-1 receptor antagonist protein antibody, Intracellular IL 1 receptor antagonist type II antibody, Intracellular interleukin 1 receptor antagonist (icIL 1ra) antibody, IRAP antibody, MGC10430 antibody, MVCD4 antibody, Type II interleukin 1 receptor antagonist antibody

UniProt: P18510

Pathways: NF-kappaB Signalweg, Hormone Transport, Cancer Immune Checkpoints